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The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Comprehensive literature review on CH4-CO2 replacement in microscale porous media
(
Elsevier B.V.
, 2018 , Article Review)
Gas production studies from natural gas hydrate reservoirs have been the subject of extensive research in recent years. Although CH4-CO2 replacement production method from gas hydrates has many advantages, the number of ...
Rational development of nanomedicines for molecular targeting in periodontal disease
(
Elsevier Ltd
, 2018 , Article Review)
Recent advances in understanding the etiology and pathogenesis of periodontal disease and polymicrobial synergy in the dysbiotic oral microbial community endorsed novel therapeutic targets and assured further improvement ...
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
(
Elsevier B.V.
, 2018 , Article Review)
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ...
Efficacy and safety of laxatives for chronic constipation in long-term care settings: A systematic review
(
Blackwell Publishing Ltd
, 2018 , Article Review)
What is known and objective: Constipation is a common disorder among long-term care (LTC) patients due to several factors. However, there are no systematic reviews investigating the use of laxatives for chronic constipation ...
Limits and possible solutions in quantum dot organic solar cells
(
Elsevier Ltd
, 2018 , Article Review)
In this review article, we present recent advancements in the field of organic photovoltaics (OPV) that have been achieved through the applications of quantum dots (QDs). We describe the leading experimental accomplishments ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
AMP-activated protein kinase as a drug target in chronic kidney disease
(
Bentham Science Publishers B.V.
, 2018 , Article Review)
Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ...
Direct Oral Anticoagulant Use in Atypical Thrombosis-Related Conditions
(
SAGE Publications Inc.
, 2018 , Article Review)
Objective: To review the published literature for evidence of the efficacy and safety of direct oral anticoagulants (DOACs) when used in the management of atypical thrombosis-related conditions. Data Sources: A comprehensive ...
Graphene-based nanopore approaches for DNA sequencing: A literature review
(
Elsevier Ltd
, 2018 , Article Review)
DNA (deoxyribonucleic acid) is the blueprint of life as it encodes all genetic information. In genetic disorder such as gene fusion, copy number variation (CNV) and single nucleotide polymorphism, DNA sequencing is used ...