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Advanced antifouling zwitterionic layer based impedimetric HER2 biosensing in human serum: Glycoprofiling as a novel approach for breast cancer diagnostics
(
Elsevier B.V.
, 2018 , Article)
There are two key novel components presented here behind identification of potential novel breast cancer (BCa) diagnostic approach: 1. application of photoimmobilizable zwitterionic hydrogels resisting non-specific protein ...
BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes
(
BioScientifica Ltd.
, 2018 , Article)
In Oman, breast cancer is most common, representing approximately more than 25% of all cancers in women. Relatively younger populations of patients (25-40 years) present surprisingly with an aggressive phenotype and advanced ...
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
(
Taylor and Francis Ltd
, 2019 , Article)
Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ...
3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy
(
Elsevier B.V.
, 2021 , Article)
The bioprinting technique with specialized tissue production allows the study of biological, physiological, and behavioral changes of cancerous and non-cancerous tissues in response to pharmacological compounds in personalized ...
A simple model for cell type recognition using 2D-correlation analysis of FTIR images from breast cancer tissue
(
Elsevier B.V.
, 2018 , Article)
Breast cancer is the second most common cancer after lung cancer. So far, in clinical practice, most cancer parameters originating from histopathology rely on the visualization by a pathologist of microscopic structures ...
Investigation of the effect of PD-L1 blockade on triple negative breast cancer cells using fourier transform infrared spectroscopy
(
MDPI AG
, 2019 , Article)
Interactions between programmed death-1 (PD-1) with its ligand PD-L1 on tumor cells can antagonize T cell responses. Inhibiting these interactions using immune checkpoint inhibitors has shown promise in cancer immunotherapy. ...
Landscape of NAT2 polymorphisms among breast cancer.
(
Elsevier Masson
, 2016 , Article)
PURPOSE:
The prevalence of phenotypes of Arylamine N-acetyltransferase-2(NAT2) gene (i.e. fast, intermediate and slow acetylators) among ethnic groups, as well as the association studies regarding NAT2 polymorphisms and ...
Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes.
(
Elsevier
, 2018 , Article)
The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with ...
Cost-effectiveness analyses of breast cancer medications use in developing countries: a systematic review
(
Taylor and Francis Ltd.
, 2020 , Article)
Background: Pharmacoeconomics is important for breast-cancer medications due to their high costs. To our knowledge, no systematic literature reviews of pharmacoeconomic studies for breast-cancer medication use are present ...
Development of point-of-care nanobiosensors for breast cancers diagnosis
(
Elsevier B.V.
, 2020 , Article)
Nanobiosensors have played a key role as portable devices in the rapid breast cancer diagnosis and in clinical medicine like point-of-care devices. However, understanding biomarkers and nanomaterials is crucial for improving ...