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Generalisability theory analyses of concept mapping assessment scores in a problem-based medical curriculum
(
Blackwell Publishing Ltd
, 2016 , Article)
Context
In problem-based learning (PBL), students construct concept maps that integrate different concepts related to the PBL case and are guided by the learning needs generated in small-group tutorials. Although an ...
Mixed Zwitterion-Based Self-Assembled Monolayer Interface for Impedimetric Glycomic Analyses of Human IgG Samples in an Array Format
(
American Chemical Society
, 2016 , Article)
An impedimetric lectin biosensor for the detection of changes in the glycan structure of antibodies isolated from human serum is here correlated with the progression of rheumatoid arthritis (RA). The biosensor was built ...
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
(
S. Karger AG
, 2016 , Conference Paper)
This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ...
Locality Sensitive Deep Learning for Detection and Classification of Nuclei in Routine Colon Cancer Histology Images
(
Institute of Electrical and Electronics Engineers Inc.
, 2016 , Article)
Detection and classification of cell nuclei in histopathology images of cancerous tissue stained with the standard hematoxylin and eosin stain is a challenging task due to cellular heterogeneity. Deep learning approaches ...
Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells
(
Spandidos Publications
, 2016 , Article)
Patients with cancer often exhibit signs of anemia as the result of the disease. Thus, cancer chemotherapies often include erythropoietin (EPO) in the regime to improve the survival rate of these patients. The aim of the ...
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
(
Springer International Publishing
, 2016 , Article Review)
Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ...
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
(
Elsevier Inc.
, 2016 , Article Review)
Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
(
Elsevier B.V.
, 2016 , Article)
This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ...
Identification of SER-PRO-CYS Peptide in Blood Serum of Multiple Sclerosis Patients
(
Bentham Science Publishers
, 2016 , Article)
Monitoring of multiple sclerosis (MS) requires additional molecular markers. Recently, we used original TCA-precipitation/extraction approach in combination with MALDI TOF/TOF mass-spectrometry and identified earlier unknown ...