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Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
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Elsevier B.V.
, 2021 , Article)
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ...
U-healthcare system: State-of-the-art review and challenges
(
SpringerLink
, 2013 , Article)
With the increase of an ageing population and chronic diseases, society becomes more health conscious and patients become "health consumers" looking for better health management. People's perception is shifting towards ...
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
(
Elsevier Inc.
, 2016 , Article Review)
Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ...
Use of the Delphi technique in pharmacy practice research
(
Elsevier Inc.
, 2022 , Article)
Consensus research methods are used in health services research to generate evidence through systematic means of measuring collective agreement and developing consensus from experts of a subject matter. Delphi technique ...
BIAN N-heterocyclic gold carbene complexes induced cytotoxicity in human cancer cells via upregulating oxidative stress
(
Asian Pacific Organization for Cancer Prevention
, 2015 , Article)
Background: Nanoparticles of gold and silver are offering revolutionary changes in the field of cancer therapy. N-heterocyclic carbene (NHC) metal complexes possess diverse biological activities and are being investigated ...
Significant Toxic Effect of Carbon Nanofibers at the Early Stage of Embryogenesis
(
NLM (Medline)
, 2020 , Article)
Implementation of carbon nanofibers (CNFs) in biomedical applications have successful outcomes, however, they are still considered as a potential hazard. We herein used avian embryos at 3 days and its chorioallantoic ...
Platelet Concentrate Treatments for Temporomandibular Disorders: A Systematic Review and Meta-analysis
(
SAGE Publications Ltd
, 2021 , Article)
Objectives: This systematic review compared platelet concentrates (PCs) versus hyaluronic acid (HA) or saline/Ringer?s solution injections as treatments of temporomandibular osteoarthritis and disc displacement in terms ...
The role of cortical perforations in allogeneic block grafting for lateral augmentation in maxilla: A randomized clinical trial
(
John Wiley and Sons Inc
, 2021 , Article)
Background: The need of decortication on the recipient site remains unclear for bone regeneration. To our knowledge, there are no human clinical trials that studied the influence of decortication on cancellous allogeneic ...
Development of a Checklist to Prevent Reconstructive Errors Made By Undergraduate Dental Students
(
Blackwell Publishing Inc.
, 2020 , Article)
Purpose: To design a checklist in order to reduce the frequency of reconstructive preventable errors (PE) performed by undergraduate dental students at McGill University. Materials and Methods: The most common PE occurring ...
Osseointegration Pharmacology: A Systematic Mapping Using Artificial Intelligence
(
Acta Materialia Inc
, 2021 , Article)
Clinical performance of osseointegrated implants could be compromised by the medications taken by patients. The effect of a specific medication on osseointegration can be easily investigated using traditional systematic ...