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EndMT regulation by small RNAs in diabetes-associated fibrotic conditions: potential link with oxidative stress
(
Frontiers Media
, 2021 , Article)
Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ dysfunction, disability, and increased mortality. ...
SARS-CoV-2 infection among primary healthcare workers: a cross- sectional study
(
GERMS
, 2021 , Article)
Healthcare workers (HCWs) are critical to the healthcare system and are at an increased risk of SARS-CoV-2 infection. They may acquire infections from the community and their work settings. To date, the majority of the ...
Ecotoxicological assessment of two surfactant on the emryonic development
(
Qatar University Press
, 2021 , Poster)
In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 ...
Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study
(
Public Library of Science
, 2021 , Article)
Background Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. Objective In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with ...
Neutralization of MERS coronavirus through a scalable nanoparticle vaccine
(
Springer Nature
, 2021 , Article)
MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). ...
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
(
Elsevier
, 2022 , Article)
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ...
Is it the time for Hepatitis E virus (HEV) Testing for Blood Donors in Qatar?
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background: HEV is the etiologic agent of acute hepatitis E. Although HEV usually causes a self-limiting infection, the disease may develop into a chronic or fulminant form of Hepatitis. Sporadic HEV infections spread in ...
Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
(
IMR Press
, 2022 , Article Review)
Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ...
Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron
(
MDPI
, 2022 , Article)
In this report, we mechanistically reveal how the Variant of Concern (VOC) SARS-CoV-2 Omicron (B.1.1.529) escapes neutralizing antibody responses, by physio-chemical characterization of this variant in comparison to the ...
Seroprevalence of herpes simplex virus types 1 and 2 in Indian and Filipino migrant populations in Qatar: a cross-sectional survey
(
World Health Organization
, 2018 , Article)
Background: The epidemiology of herpes simplex virus infections is of growing interest but
information on its seroprevalence in many countries is scarce.
Aims: This study aimed to measure the seroprevalence of herpes ...