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Now showing items 11-17 of 17
Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies.
(
taylor and francis online
, 2023 , Article)
Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ...
Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer
(
Institute for Ionics
, 2023 , Article Review)
Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene expression and protein functions and are implicated in various biological processes including cancer. Notably, breast cancer has a ...
Potential Therapeutic Targets of Resveratrol in the Prevention and Treatment of Pulmonary Fibrosis
(
IMR Press Limited
, 2023 , Article)
Pulmonary fibrosis (PF) is a feared component in over 200 interstitial pulmonary diseases, which are characterized by increased alveolar wall thickness, excessive scarring, and aberrant extracellular matrix restructuring ...
Single-cell transcriptomic analysis reveals crucial oncogenic signatures and its associative cell types involved in gastric cancer
(
Springer Nature
, 2023 , Article)
The intricate association of oncogenic markers negatively impacts accurate gastric cancer diagnosis and leads to the proliferation of mortality rate. Molecular heterogeneity is inevitable in determining gastric cancer's ...
Identification of Potential Inhibitors Targeting GTPase-Kirsten RAt Sarcoma Virus (K-Ras) Driven Cancers via E-Pharmacophore-Based Virtual Screening and Drug Repurposing Approach
(
IMR Press Limited
, 2023 , Article)
Background: Mutations in the K-Ras gene are among the most frequent genetic alterations in various cancers, and inhibiting RAS signaling has shown promising results in treating solid tumors. However, finding effective drugs ...
Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature
(
Elsevier
, 2023 , Article Review)
Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ...
Airway and Oral microbiome profiling of SARS-CoV-2 infected asthma and non-asthma cases revealing alterations-A pulmonary microbial investigation
(
NLM (Medline)
, 2023 , Article)
New evidence strongly discloses the pathogenesis of host-associated microbiomes in respiratory diseases. The microbiome dysbiosis modulates the lung's behavior and deteriorates the respiratory system's effective functioning. ...