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Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin-angiotensin-aldosterone system (RAAS) dysregulation
(
Elsevier Ireland Ltd
, 2022 , Article)
The rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID?19), has had a dramatic negative impact on public health and economies worldwide. Recent studies ...
Bioengineered microfluidic blood-brain barrier models in oncology research
(
Neoplasia Press, Inc.
, 2021 , Article)
Metastasis is the major reason for most brain tumors with up to a 50% chance of occurrence in patients with other types of malignancies. Brain metastasis occurs if cancer cells succeed to cross the ?blood-brain barrier? ...
Development of nitric oxide releasing visible light crosslinked gelatin methacrylate hydrogel for rapid closure of diabetic wounds
(
Elsevier Masson s.r.l.
, 2021 , Article)
Management of non-healing and slow to heal diabetic wounds is a major concern in healthcare across the world. Numerous techniques have been investigated to solve the issue of delayed wound healing, though, mostly unable ...
Stromal cell-derived factor loaded co-electrospun hydrophilic/hydrophobic bicomponent membranes for wound protection and healing
(
Royal Society of Chemistry
, 2020 , Article)
Chronic wounds are one of the key concerns for people with diabetes, frequently leading to infections and non-healing ulcers, and finally resulting in the amputation of limbs/organs. Stromal cell-derived factor 1 (SDF1) ...
Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
(
Springer
, 2019 , Article)
In this study, a set of polylactic acid (PLA)/polyphenol extracted from date palm fruit (DP) blends were prepared by electrospinning process to be used as cell culture scaffolds for tissue engineering applications. For ...
Structure and Rheological Properties of Bovine Aortic Heart Valve and Pericardium Tissue: Implications in Bioprosthetic and Tissue-Engineered Heart Valves
(
Hindawi Limited
, 2019 , Article)
Heart valve (HV) diseases are among the leading causes of cardiac failure and deaths. Of the various HV diseases, damaged HV leaflets are among the primary culprits. In many cases, impaired HV restoration is not always ...
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
(
Springer
, 2022 , Article Review)
EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ...
A Novel Machine Learning Approach for Severity Classification of Diabetic Foot Complications Using Thermogram Images
(
MDPI
, 2022 , Article)
Diabetes mellitus (DM) is one of the most prevalent diseases in the world, and is correlated to a high index of mortality. One of its major complications is diabetic foot, leading to plantar ulcers, amputation, and death. ...
Potential of antibody-drug conjugates (ADCs) for cancer therapy
(
BioMed Central Ltd
, 2022 , Article Review)
The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. ...
Role of Graphene Oxide in Bacterial Cellulose−Gelatin Hydrogels for Wound Dressing Applications
(
American Chemical Society
, 2022 , Article)
Biopolymer-based hydrogels have several advantages, including robust mechanical, high biocompatibility, and excellent properties. These hydrogels can be ideal wound dressing materials and advantageous to repair and regenerate ...