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Synthesis and Spectroscopic Studies ofAtenolol Derivatives with Enhanced Lipophilicity as Potential Prodrugs
( Qatar University , 2002 , Article)
Atenolol, a selective pi-adrenoceptor blocking agent is characterized by its low bioavailability. A number of atenolol prodrugs were synthesized to improve its lipid solubility and hence bioavailability. These compounds ...