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Expression of sperm PLC? and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion
(
Elsevier Ltd
, 2018 , Article)
Globozoospermia is characterized by the presence of 100% acrosomeless round-headed spermatozoa in an ejaculate. Failed fertilization after intracytoplasmic sperm injection (ICSI) is commonly reported for globozoospermic ...
Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?
(
Company of Biologists Ltd
, 2018 , Article)
The cardiac muscle ryanodine receptor-Ca2+ release channel (RyR2) constitutes the sarcoplasmic reticulum (SR) Ca2+ efflux mechanism that initiates myocyte contraction, while cardiac myosin-binding protein-C (cMyBP-C; also ...
Phospholipase C zeta and calcium oscillations at fertilisation: The evidence applications and further questions
(
Elsevier Ltd
, 2018 , Article)
Oocyte activation is a fundamental event at mammalian fertilisation, initiated by a series of characteristic calcium (Ca2+) oscillations in mammals. This characteristic pattern of Ca2+ release is induced in a species-specific ...