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TRAF6-mediated ubiquitination of NEMO requires p62/sequestosome-1
(
Elsevier Ltd.
, 2014 , Article)
The atypical protein kinase C-interacting protein p62/sequestosome-1 (p62) has emerged as a crucial molecule in a variety of cellular functions due to its involvement in various signaling mechanisms. p62 has been implicated ...
In-frame fusion of SUMO1 enhances βarrestin2's association with activated GPCRs as well as with nuclear pore complexes
(
Elsevier
, 2020 , Article)
Small ubiquitin like modifier (SUMO) conjugation or SUMOylation of βarrestin2 promotes its association with the clathrin adaptor protein AP2 and facilitates rapid β2 adrenergic receptor (β2AR) internalization. However, ...
Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells.
(
BMC
, 2021 , Article Review)
Protein ubiquitination is one of the most crucial posttranslational modifications responsible for regulating the stability and activity of proteins involved in homeostatic cellular function. Inconsistencies in the ...
Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.
(
Humana Press, New York, NY
, 2019 , Book chapter)
Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ...