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Rifampin-warfarin interaction in a mitral valve replacement patient receiving rifampin for infective endocarditis: a case report
(
SpringerOpen
, 2016 , Article)
Warfarin therapy is associated with many drug interactions that may cause a significant alteration in its anticoagulant effect. Rifampin is a widely used antimicrobial that has major interactions with several medications ...
Telephone versus office-based management of warfarin: Impact on international normalized ratios and outcomes
(
Springer-Verlag Tokyo
, 2014 , Article)
Studies have concluded that telephone-based management of warfarin is an effective alternative to in-office management. High rates of patient and physician satisfaction have been reported with telephone-based monitoring. ...
THE EFFECT OF GENETIC AND NON-GENETIC FACTORS ON WARFARIN DOSE VARIABILITY IN QATARI POPULATION
(2018 , Master Thesis)
Introduction: Genetic and non-genetic factors were shown to affect warfarin dosing; however, their effect may vary from one population to the other. No previous studies were conducted on the Qatari population to elucidate ...
Effect of SAMe-TT2R2 score and genetic polymorphism on the quality of anticoagulation control in Qatari patients treated with warfarin.
(
Springer Nature
, 2020 , Article)
There is no strong evidence on pharmacogenetics role on the quality of INR control after the initiation phase and on the maintenance of stable INR on the long term as measured by the time in therapeutic range (TTR). The ...
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
Cancer-Associated Venous Thromboembolism
(
Springer Healthcare
, 2016 , Article Review)
Cancer patients are at high risk for venous thromboembolism (VTE) which is considered the second leading cause of death among this population. Both cancer and cancer treatment increase this risk. Since the risk of VTE is ...
Trends in oral anticoagulant use in Qatar: a 5-year experience
(
Springer New York LLC
, 2017 , Article)
In Qatar, dabigatran was introduced in 2011 followed by rivaroxaban in 2014. In this study, we aim to explore the trends in oral anticoagulant use in Qatar over the past 5 years and to what extent did DOACs replace warfarin. ...
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
(
Springer International Publishing
, 2017 , Article Review)
Background
Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood.
Objectives
The objective of this systematic review was to ...
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
(
Blackwell Publishing Ltd
, 2016 , Article)
Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ...
Evaluation of pharmacist-based compared to doctor-based anticoagulation management in Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives For over 60 years, warfarin has been the mainstay anticoagulant used in the outpatient setting for the prevention and treatment of a wide variety of thromboembolic clinical conditions. ...