Search
Now showing items 1-10 of 19
Instrumentation of Flow-Through USP IV Dissolution Apparatus to Assess Poorly Soluble Basic Drug Products: a Technical Note
(
Springer New York LLC
, 2016 , Article)
Supersaturation and precipitation are common limitations encountered especially with poorly soluble basic drugs. The aims of this work were to explore the pattern of dissolution and precipitation of poorly soluble basic ...
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
(
Taylor and Francis Ltd
, 2016 , Article)
Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ...
Sensitive detection and glycoprofiling of a prostate specific antigen using impedimetric assays
(
Royal Society of Chemistry
, 2016 , Article)
This study presents a proof-of-concept for the development of an impedimetric biosensor for ultra-sensitive glycoprofiling of prostate specific antigen (PSA). The biosensor exhibits three unique characteristics: (1) analysis ...
Flavonol-carbon nanostructure hybrid systems: A DFT study on the interaction mechanism and UV/Vis features
(
Royal Society of Chemistry
, 2016 , Article)
Flavonols are a class of natural compounds with potential biological and pharmacological applications. They are also natural pigments responsible for the diversity of colors in plants. Flavonols offer the possibility of ...
Preparation and characterization of green graphene using grape seed extract for bioapplications
(
Elsevier Ltd
, 2016 , Article)
The development of functionalized graphene materials concerning health and environmental aspects via green approaches is currently the most recent topic in the field of nanoscience and nanotechnology. Herein, we report the ...
Electroactive and Optically Adaptive Bionanocomposite for Reconfigurable Microlens
(
American Chemical Society
, 2016 , Article)
This paper introduces an electroactive bionanocomposite based on poly(diethylene glycol adipate) (PDEGA) and cellulose nanocrystals (CNCs). The bionanocomposites were made using CNCs extracted from cotton and by optimizing ...
Mixed Zwitterion-Based Self-Assembled Monolayer Interface for Impedimetric Glycomic Analyses of Human IgG Samples in an Array Format
(
American Chemical Society
, 2016 , Article)
An impedimetric lectin biosensor for the detection of changes in the glycan structure of antibodies isolated from human serum is here correlated with the progression of rheumatoid arthritis (RA). The biosensor was built ...
Graphene oxide-based electrochemical label-free detection of glycoproteins down to aM level using a lectin biosensor
(
Royal Society of Chemistry
, 2016 , Article)
A label-free ultrasensitive impedimetric biosensor with lectin immobilised on graphene oxide (GO) for the detection of glycoproteins from 1 aM is shown here. This is the first time a functional lectin biosensor with lectin ...
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
(
S. Karger AG
, 2016 , Conference Paper)
This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ...
Isolation and Physicochemical Characterization of Laccase from Ganoderma lucidum-CDBT1 Isolated from Its Native Habitat in Nepal
(
Hindawi Limited
, 2016 , Article)
At present, few organisms are known to and capable of naturally producing laccases and white rot fungi are one such group. In the
present study, three fungal species, namely, Ganoderma lucidum-CDBT1, Ganoderma japonicum, ...