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    miR-21 mimic blocks obesity in mice: A novel therapeutic option 

    Lhamyani, Said; Gentile, Adriana-Mariel; Giráldez-Pérez, Rosa M; Feijóo-Cuaresma, Mónica; Romero-Zerbo, Silvana Yanina; Clemente-Postigo, Mercedes; Zayed, Hatem; Olivera, Wilfredo Oliva; Bermúdez-Silva, Francisco Javier; Salas, Julián; Gómez, Carlos López; Hmadcha, Abdelkrim; Hajji, Nabil; Olveira, Gabriel; Tinahones, Francisco J; El Bekay, Rajaa... more authors ... less authors ( Elsevier , 2021 , Article)
    MicroRNAs (miRNAs) are promising drug targets for obesity and metabolic disorders. Recently, miRNA mimics are providing a unique mechanism of action that guides the process for drug development and sets out the context of ...
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    Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene 

    Moseilhy, Ahmed; Hassan, Magdy M.; El Abd, Heba S. A.; Mohammad, Shaimaa A.; El Bekay, Rajaa; Abdel-Motal, Ussama M.; Ouhtit, Allal; Zaki, Osama K.; Zayed, Hatem... more authors ... less authors ( Springer US , 2016 , Article)
    Abstract To characterize an Egyptian patient with glutaric acidemia type I (GA I) and to identify the causative mutation( s) that may be responsible for the disease phenotype. MRI was performed on the patient using the ...
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    miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes. 

    Gentile, Adriana-Mariel; Lhamyani, Said; Coín-Aragüez, Leticia; Clemente-Postigo, Mercedes; Oliva Olivera, Wilfredo; Romero-Zerbo, Silvana-Yanina; García-Serrano, Sara; García-Escobar, Eva; Zayed, Hatem; Doblado, Esther; Bermúdez-Silva, Francisco-Javier; Murri, Mora; Tinahones, Francisco J; El Bekay, Rajaa... more authors ... less authors ( Wiley , 2019 , Article)
    This study aimed to analyze the potential association of different microRNA (miRNA) molecules with both type 2 diabetes (T2D) and obesity and determine their target genes. Quantitative PCR was used to analyze the miR-20b, ...
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    Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World 

    Doss, C. George Priya; Alasmar, Dima R.; Bux, Reem I.; Sneha, P.; Bakhsh, Fadheela Dad; Al-Azwani, Iman; El Bekay, Rajaa; Zayed, Hatem... more authors ... less authors ( Nature Publishing Group , 2016 , Article)
    A systematic search was implemented using four literature databases (PubMed, Embase, Science Direct and Web of Science) to capture all the causative mutations of Glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDD) ...
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    An Arab registry for type 1 diabetes: global benefits for type 1 diabetes patients 

    Zayed, Hatem; Ouhtit, Allal; El Bekay, Rajaa ( Taylor & Francis , 2016 , Article)
    BACKGROUND: The Arab world encompasses twenty-two Arabic-speaking countries, where the rate of consanguinity can exceed 50%. Type 1 diabetes (T1D), a chronic disorder that requires lifelong treatment, is believed to be ...
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    Two patients with Canavan disease and structural modeling of a novel mutation. 

    Zaki, Osama K; Krishnamoorthy, Navaneethakrishnan; El Abd, Heba S; Harche, Soumaya A; Mattar, Reem A; Al Disi, Rana S; Nofal, Mariam Y; El Bekay, Rajaa; Ahmed, Khalid A; George Priya Doss, C; Zayed, Hatem... more authors ... less authors ( Springer US , 2017 , Article)
    Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme, which catalyzes the hydrolysis ...
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    RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR 

    Gentile, Adriana-Mariel; Lhamyani, Said; Coín-Aragüez, Leticia; Oliva-Olivera, Wilfredo; Zayed, Hatem; Vega-Rioja, Antonio; Monteseirin, Javier; Romero-Zerbo, Silvana-Yanina; Tinahones, Francisco-José; Bermúdez-Silva, Francisco-Javier; El Bekay, Rajaa... more authors ... less authors ( Public Library of Science (PLoS) , 2016 , Article)
    Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ...
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    Myocardial ischemic subject's thymus fat: A novel source of multipotent stromal cells 

    Oliva-Olivera, Wilfredo; Coin-Araguez, Leticia; Salas, Julian; Lhamyani, Said; Gentile, Adriana-Mariel; Garcia, Esteban Sarria; Hmadcha, Abdelkrim; Zayed, Hatem; Vega-Rioja, Antonio; Tinahones, Francisco J.; El Bekay, Rajaa... more authors ... less authors ( Public Library of Science , 2015 , Article)
    Objective Adipose Tissue Stromal Cells (ASCs) have important clinical applications in the regenerative medicine, cell replacement and gene therapies. Subcutaneous Adipose Tissue (SAT) is the most common source of these ...

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    • El Bekay, Rajaa (4)
    • El Bekay, Rajaa (4)
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      Article (8)
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      adipose tissue (2) Arab countries (2) MRI (2) 5' nucleotidase (1) ... View More
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