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Landscape of NAT2 polymorphisms among breast cancer.
(
Elsevier Masson
, 2016 , Article)
PURPOSE:
The prevalence of phenotypes of Arylamine N-acetyltransferase-2(NAT2) gene (i.e. fast, intermediate and slow acetylators) among ethnic groups, as well as the association studies regarding NAT2 polymorphisms and ...
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
(
Taylor and Francis Ltd
, 2019 , Article)
Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ...
Apocrine Carcinoma
(
Springer, Cham
, 2017 , Book chapter)
Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification
of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” ...
Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes.
(
Elsevier
, 2018 , Article)
The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with ...
BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes
(
BioScientifica Ltd.
, 2018 , Article)
In Oman, breast cancer is most common, representing approximately more than 25% of all cancers in women. Relatively younger populations of patients (25-40 years) present surprisingly with an aggressive phenotype and advanced ...
Nanoparticle-mediated targeted drug delivery for breast cancer treatment
(
Elsevier B.V.
, 2019 , Article Review)
Breast cancer (BC) is the most common malignancy in women worldwide, and one of the deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are surgery followed by chemotherapy or radiotherapy. ...
A simple model for cell type recognition using 2D-correlation analysis of FTIR images from breast cancer tissue
(
Elsevier B.V.
, 2018 , Article)
Breast cancer is the second most common cancer after lung cancer. So far, in clinical practice, most cancer parameters originating from histopathology rely on the visualization by a pathologist of microscopic structures ...
Advanced antifouling zwitterionic layer based impedimetric HER2 biosensing in human serum: Glycoprofiling as a novel approach for breast cancer diagnostics
(
Elsevier B.V.
, 2018 , Article)
There are two key novel components presented here behind identification of potential novel breast cancer (BCa) diagnostic approach: 1. application of photoimmobilizable zwitterionic hydrogels resisting non-specific protein ...
PD-L1 status in breast cancer: Current view and perspectives.
(
Elsevier
, 2019 , Article)
Breast cancer was traditionally not considered a particularly immunogenic tumor. However, recent developments have shown that some aggressive triple-negative breast cancers are immunogenic, exhibit a resistance to chemotherapy ...
Exposure to EGF and 17-estradiol irreversibly affects the proliferation and transformation of MCF7 cells but is not sufficient to promote tumor growth in a xenograft mouse model upon withdrawal of exposure
(
Spandidos Publications
, 2018 , Article)
Epidermal growth factor (EGF) and estrogen are potent regulators of breast tumorigenesis. Their short‑term actions on human breast epithelial cells have been investigated extensively. However, the consequence of a long‑term ...