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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
(
Springer International Publishing
, 2017 , Article Review)
Background
Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood.
Objectives
The objective of this systematic review was to ...
A systematic review of the use of simulation and reflection as summative assessment tools to evaluate student outcomes following interprofessional education activities.
(
Taylor and Francis
, 2022 , Article Review)
Despite the increasing emphasis on interprofessional education (IPE) in curricula and the potential benefits for student learning, there appears to be a lack of evidence directing authentic and accurate assessment of ...
The Therapeutic Effects of Camel Milk: A Systematic Review of Animal and Human Trials
(
SAGE Publications Ltd
, 2016 , Article Review)
The clinical effectiveness and value of camel milk as a therapeutic agent is currently unclear. MEDLINE (1946 to March 2016), EMBASE (1974 to March 2016), and Google Scholar were searched using the following terms: milk, ...
A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies
(
Springer International Publishing
, 2017 , Article Review)
Meropenem is a carbapenem antibiotic that exhibits time-dependent bactericidal activity, traditionally dosed intravenously at 1�g every 8�h. In order to maximize its pharmacodynamic activity and reduce costs, an alternative ...
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
(
Springer International Publishing
, 2016 , Article Review)
Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ...
Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis
(
SAGE Publications Inc.
, 2017 , Article Review)
Objective: To summarize and evaluate the existing literature regarding medications to treat Parkinson's disease (PD) psychosis. Data Sources: MEDLINE (1946 to March 2017), EMBASE (1980 to March 2017), CINAHL (1982 to March ...
A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
(
SAGE Publications Inc.
, 2017 , Article Review)
Background/Objective: To improve antimicrobial utilization, development and implementation of antimicrobial stewardship programs in the emergency department (ED) has been recommended. The primary objective of this review ...
A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
(
Springer-Verlag France
, 2017 , Article Review)
Genetic variability in drug-metabolizing enzymes and drug transporters is known to influence the pharmacokinetics of many drugs. Antimalarial drugs are a class of agents known to utilize metabolic and elimination pathways ...
Creation of an inventory of quality markers used to evaluate pharmacokinetic literature: A systematic review
(
Wiley
, 2021 , Article Review)
What is known and objective: Robust critical appraisal tools for clinical pharmacokinetic studies are limited. Before development of such a tool is possible, quality markers (items deemed important for credibility of study ...