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Optimal control of midazolam infusion for post operative patients in intensive care units
(
Wiley-Blackwell
, 2015 , Article)
The critical task of anesthesia administration demands optimal drug titration by considering patient-specific features and sedation requirements. Though there exist several sedation assessment monitors, physicians still ...
A Nonovershooting Controller with Integral Action for Multi-input Multi-output Drug Dosing Control ?
(
Elsevier B.V.
, 2018 , Conference Paper)
In this paper, a nonovershooting tracking controller is proposed for the continuous infusion of multiple drugs that have interactive effects. The proposed controller design method exploits the freedom of eigenstructure ...
Direct adaptive disturbance rejection control for sedation and analgesia
(
IEEE Computer Society
, 2014 , Conference Paper)
Patient care in intensive care units involves the combined administration of several drugs. Apart from the desired drug effect, often such drugs disturb other physiological functions of the patient. Control strategies based ...
Optimal control of midazolam infusion for post operative patients in intensive care units
(
Institute of Electrical and Electronics Engineers Inc.
, 2013 , Conference Paper)
The critical task of anesthesia administration demands minimal drug titration by considering patient specific features and sedation requirements. Though there exist several sedation assessment monitors, physicians still ...
A nonovershooting tracking controller for simultaneous infusion of anesthetics and analgesics
(
Elsevier Ltd
, 2019 , Article)
In this paper, a nonovershooting tracking controller is proposed for the continuous infusion of multiple drugs that have interactive effects. The proposed controller design method exploits the freedom of eigenstructure ...
Optimal adaptive control of drug dosing using integral reinforcement learning
(
Elsevier Inc.
, 2019 , Article)
In this paper, a reinforcement learning (RL)-based optimal adaptive control approach is proposed for the continuous infusion of a sedative drug to maintain a required level of sedation. To illustrate the proposed method, ...