Browsing College of Dental Medicine by Subject "rat"
Now showing items 1-7 of 7
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Biomimetic trace metals improve bone regenerative properties of calcium phosphate bioceramics
( John Wiley and Sons Inc , 2021 , Article)The bone regenerative capacity of synthetic calcium phosphates (CaPs) can be enhanced through the enrichment with selected metal trace ions. However, defining the optimal elemental composition required for bone formation ... -
Differences in platelet-rich plasma composition influence bone healing
( John Wiley and Sons Inc , 2021 , Article)Aim: Platelet-rich plasma (PRP) is an autologous blood-derived material that has been used to enhance bone regeneration. Clinical studies, however, reported inconsistent outcomes. This study aimed to assess the effect of ... -
Multiscale structural evolution of citrate-triggered intrafibrillar and interfibrillar mineralization in dense collagen gels
( Academic Press Inc. , 2020 , Article)The mineralized extracellular matrix of bone is an organic?inorganic nanocomposite consisting primarily of carbonated hydroxyapatite, fibrous type I collagen, noncollagenous proteins, proteoglycans, and diverse biomolecules ... -
Postoperative administration of the acetylcholinesterase inhibitor, donepezil, interferes with bone healing and implant osseointegration in a rat model
( MDPI AG , 2020 , Article)Donepezil is an acetylcholinesterase inhibitor commonly used to treat mild to moderate Alzheimer?s disease. Its use has been associated with increased bone mass in humans and animals. However, the effect of postoperative ... -
Ranitidine Impairs Bone Healing and Implant Osseointegration in Rats' Tibiae
( W.B. Saunders , 2020 , Article)Purpose: Ranitidine has been found to have an impact on bone metabolism by suppressing osteoclastogenesis. We hypothesized that the use of ranitidine would impair bone healing and implant osseointegration. This study ... -
The effect of aging on the bone healing properties of blood plasma
( Elsevier Ltd , 2021 , Article)Objectives: Age-related changes in blood composition have been found to affect overall health. Thus, this study aimed to understand the effect of these changes on bone healing by assessing how plasma derived from young and ... -
The Role of Surface Chemistry in the Osseointegration of PEEK Implants
( American Chemical Society , 2022 , Article)Poly(etheretherketone) (PEEK) implants suffer from poor osseointegration because of chronic inflammation. In this study, we hypothesized that adding NH2and COOH groups to the surface of PEEK could modulate macrophage ...