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Ranitidine Impairs Bone Healing and Implant Osseointegration in Rats' Tibiae
(
W.B. Saunders
, 2020 , Article)
Purpose: Ranitidine has been found to have an impact on bone metabolism by suppressing osteoclastogenesis. We hypothesized that the use of ranitidine would impair bone healing and implant osseointegration. This study ...
Chronotherapy of Non-Steroidal Anti-Inflammatory Drugs May Enhance Postoperative Recovery
(
Nature Research
, 2020 , Article)
Postoperative pain relief is crucial for full recovery. With the ongoing opioid epidemic and the insufficient effect of acetaminophen on severe pain; non-steroidal anti-inflammatory drugs (NSAIDs) are heavily used to ...
Postoperative administration of the acetylcholinesterase inhibitor, donepezil, interferes with bone healing and implant osseointegration in a rat model
(
MDPI AG
, 2020 , Article)
Donepezil is an acetylcholinesterase inhibitor commonly used to treat mild to moderate Alzheimer?s disease. Its use has been associated with increased bone mass in humans and animals. However, the effect of postoperative ...