تصفح Master in Pharmacy حسب العنوان
السجلات المعروضة 37 -- 56 من 62
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HYPERTENSION MANAGEMENT AND PRESCRIBING PRACTICES IN PRIMARY HEALTHCARE SETTINGS IN QATAR: A MULTI-METHODS
(2023 , Master Thesis)Background: The use of antihypertensive medications controls blood pressure (BP) and reduces the incidence of complications. This study explored the prescribing patterns and trends of antihypertensive medications utilization, ... -
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
(2020 , Master Thesis)Poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery systems and gene transfection as drug carriers. They also exert several biological effects including modulating gene expression and interfering with ... -
IMPACT OF SGLT2 INHIBITORS ON CKD PROGRESSION IN DIABETIC PATIENTS IN QATAR A RETROSPECTIVE COHORT STUDY
(2023 , Master Thesis)Background: The risk of end-stage renal disease rises is based on the estimated glomerular filtration rate (eGFR) reduction. Even though multiple large-scale clinical trials have demonstrated the preventive benefits of ... -
IMPLEMENTING LEARNING FROM CONTINUOUS PROFESSIONAL DEVELOPMENT ACTIVITIES: A QUALITATIVE STUDY OF PHARMACISTS AND NURSES' BEHAVIORS USING COM-B AND TDF
(2025 , Master Thesis)Introduction: Continuing Professional Development (CPD) is an approach for health professionals to maintain knowledge and competence and can contribute to improving delivery of care. However, there is a lack of studies ... -
In Vitro & In Vivo Characterization of Tableted Spray-Congealed Lipid Microparticles for Extended Release of Vildagliptin
(2016 , Master Thesis)Vildagliptin (VG), a drug used for treatment of type 2 diabetes, is soluble in water and currently marketed as an instantaneous release tablet that is administered twice daily. VG is not available as an extended release ... -
INVESTIGATING THE ROLE OF THE ARYL HYDROCARBON RECEPTOR AND BCL-2 FAMILY PROTEINS IN OVARIAN CANCER STEM CELLS DEVELOPMENT AND CHEMORESISTANCE
(2024 , Dissertation)Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. This could be endorsed ... -
Medication-Related Burden among Patients with Chronic Disease Conditions: Perspectives of Patients attending Non-Communicable Disease Clinics in a Primary Healthcare Setting in Qatar
(2017 , Master Thesis)This study aimed to adapt a medication-related burden instrument, the Living with Medicines Questionnaire (LMQ), into the Arabic context, report the psychometric properties of the Arabic version, and assess the burden ... -
MODULATION OF THE MOLECULAR EXPRESSION AND FUNCTION OF BCL-2 FAMILY PROTEINS BY THE ARYL HYDROCARBON RECEPTOR IN BREAST CANCER STEM CELLS OF THE MDA-MB-231
(2021 , Master Thesis)Breast cancer (BC) is a frequently occurring neoplasm in women and is a second major cause of cancer related deaths. Despite the remarkable advancements in the understanding of BC and its treatments, the diseases still ... -
MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(2021 , Master Thesis)Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ... -
Multi-Criteria Decision Analytic Model for the Comparative Formulary Inclusion of Direct Oral Anticoagulant in Qatar
(2020 , Master Thesis)Aim: The formulary inclusion of direct oral anticoagulant (DOACs) in the government hospital health services in Qatar is not comparative or restricted. Requests to include a DOAC in the formulary are typically accepted ... -
Nano Liposomal Formulation for A Novel Chalcone Compound as A Potential Anticancer Delivery System for Triple-Negative Breast Cancer
(2024 , Master Thesis)Triple negative breast cancer is the most aggressive type of breast malignancy accounting for 15-20% of all breast cancer cases. Treatment of TNBC remains limited, with a high risk of relapse and metastasis to other organs. ... -
Pharmacoeconomics Evaluation of the Systemic Antifungal Posaconazole for Prophylaxis against Invasive Fungal Infections among Immunocompromised Cancer Patients in Qatar
(2018 , Master Thesis)The immunocompromised hematologic malignancy patients, at the National Center for Cancer Care (NCCCR) in Qatar, receive the antifungal posaconazole for prophylaxis as systemic prophylaxis against invasive fungal infections ... -
PRODUCTION OF LETROZOLE-LOADED MONODISPERSE POLYMERIC-BASED MICROPARTICLES FOR BREAST CANCER THERAPY
(2017 , Master Thesis)Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. However, due to its adverse effects this study was designed to investigate the feasibility of producing ... -
PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
(2017 , Master Thesis)Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ... -
Relationship between the Stages of Change and Medication Adherence in Patients with Type 2 Diabetes Mellitus in a Primary Health Care Setting in Qatar
(2016 , Master Thesis)Background: Non-adherence to medications is a major concern among patients with type 2 diabetes mellitus (T2DM). Failure to achieve positive health-related outcomes could be associated with non-adherence. Medication ... -
THE ROLE OF P90 RIBOSOMAL S6 KINASE AND AUTOPHAGY IN SUNITINIB AND PONATINIB-INDUCED CARDIOTOXICITY
(2019 , Master Thesis)In recent years, the paradigm cancer management has shifted towards a targeted approach. Among the newly targeted anticancer therapies are ponatinib and sunitinib, small molecules tyrosine kinase inhibitors (TKIs), used ... -
Sleep Patterns among University Students and Insomnia Management in Primary Care Settings in Qatar: A Two-Phase Investigation
(2020 , Master Thesis)Insomnia is a public health concern that affects approximately a third of adult population worldwide. The aim of this research was to investigate insomnia and its management among university students and primary care ... -
STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJURY
(2015 , Master Thesis)Diabetic nephropathy (DN) is the leading cause of end stage renal disease, and one of the most serious microvascular complications of diabetes mellitus. Increase in the shift of glucose into the aldose reductase pathway ... -
Strengthening the Quality of Clinical Pharmacokinetic Studies: Development and Validation of a Critical Appraisal Tool For Clinical Pharmacokinetic Research
(2020 , Master Thesis)Background: Critical appraisal process is central to the practice of evidence-based medicine that aids in assessing the quality of the published scientific knowledge. To our knowledge, there is no critical appraisal ... -
SUCCINYLATED CURCUMIN LOADED IN MANNOSYLATED CHITOSAN NANOPARTICLES FOR COLON CANCER THERAPY
(06-2 , Master Thesis)Colon cancer (CRC) is the second leading cause of death and the third most diagnosed type worldwide. Although curcumin (CUR) has potent anticancer activity, it suffers from low solubility, bioavailability, and instability. ...
