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Cost-effectiveness Analysis of Ibuprofen versus Indomethacin or Paracetamol for the Treatment of Patent Ductus Arteriosus in Preterm Neonates
(Pharmacy, 2021 , Master Thesis)
Objective: This thesis sought to evaluate the cost-effectiveness of oral paracetamol and intravenous (IV) indomethacin as alternatives to ibuprofen for patent ductus arteriosus (PDA) in neonates in Hamad Medical Corporation ...
CLINICAL AND PHARMACOECONOMIC ANALYSES OF CDK4/6 INHIBITORS USE IN STAGE IV BREAST CANCER FEMALES IN THE STATE OF QATAR: A COMPARATIVE RETROSPECTIVE OBSERVATIONAL STUDY WITH COST-EFFECTIVENESS AND COST-UTILITY ANALYSES
(Pharmacy, 2021 , Master Thesis)
Introduction: Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are indicated in the first-line treatment of hormonal receptor positive and HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although phase III ...
MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(Pharmacy, 2021 , Master Thesis)
Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ...
MODULATION OF THE MOLECULAR EXPRESSION AND FUNCTION OF BCL-2 FAMILY PROTEINS BY THE ARYL HYDROCARBON RECEPTOR IN BREAST CANCER STEM CELLS OF THE MDA-MB-231
(Pharmacy, 2021 , Master Thesis)
Breast cancer (BC) is a frequently occurring neoplasm in women and is a second major cause of cancer related deaths. Despite the remarkable advancements in the understanding of BC and its treatments, the diseases still ...
COMMUNITY PHARMACISTS' SELF-PERCEIVED COMPETENCY, AND ENABLERS, AND BARRIERS TOWARDS THE MANAGEMENT OF COMMON MINOR AILMENTS IN QATAR
(Pharmacy, 2021 , Master Thesis)
The study aimed to assess community pharmacists' self-perceived competency, and enablers and barriers towards managing common minor ailments in Qatar, and its predictors. A cross-sectional study, with pretested questionnaires, ...
A COST-EFFECTIVENESS ANALYSIS FOR HIGH VERSUS LOW DOSE CAFFEINE FOR THE TREATMENT OF APNEA IN NEONATAL INTENSIVE CARE UNIT
(Pharmacy, 2021 , Master Thesis)
Objective: This thesis sought to evaluate the cost effectiveness of high dose (HD) caffeine as alternative therapy over the standard low dose (LD) caffeine for apnea of prematurity (AOP) in neonates, in Hamad Medical ...
ASSESSMENT OF ADHERENCE, BARRIERS AND STRENGTHS TO ADHERENCE AMONG ADOLESCENTS WITH TYPE 1 DIABETES IN QATAR: PERSPECTIVES OF PATIENTS AND THEIR CAREGIVERS
(Pharmacy, 2021 , Master Thesis)
Background: Metabolic control among adolescents with type 1 diabetes mellitus (T1DM) is generally poor. Non-adherence is one of the contributors to this poor glycemic control, leading to high complication rates. The objective ...
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
(Pharmacy, 2021 , Dissertation)
The aim of this Ph.D. was to evaluate the periprocedural anticoagulation management of patients receiving warfarin in Qatar clinically and economically. In addition, exploring the clinical and economic impact of genetic ...
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONE ANALOGS AS POTENTIAL THERAPEUTIC AGENTS FOR CASTRATION RESISTANT PROSTATE CANCER
(Pharmacy, 2021 , Master Thesis)
Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ...
Surface Coating of Carbon Nanofiber by Mesoporous Silica: a Promising Strategy to Reduce its Toxicity during Embryogenesis
(Pharmacy, 2021 , Master Thesis)
Although carbon nanofibers (CNFs) have been implicated in biomedical
applications, they are still considered as a potential hazard. Conversely, mesoporous
silica nanoparticles are generally considered as a suitable and ...