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ECONOMIC EVALUATION OF DIABETIC NEUROPATHY MONOTHERAPY FOLLOWED BY COMBINATION THERAPY TREATMENT
(Pharmacy, 2024 , Master Thesis)
Objective: To summarize the literature evidence towards the efficacy and safety of diabetic neuropathy (DNP) treatments, and to assess the cost-effectiveness among the DNP treatment regimens in Qatar, including the use of ...
Developing Pharmacist-Led Anticoagulation Clinics in Primary Care Settings: A Multi-Phase Mixed-Methods Study
(Pharmacy, 2024 , Master Thesis)
Background: Primary care is an integral part of the healthcare system. Patients have better accessibility and continuity of care. However, studies have reported low-quality warfarin management in these settings. Pharmacist-led ...
The Cytotoxicity Of “Al-Siddir” Tree “Ziziphus Spina Christi” Methanolic Leaves Extract on Her-2 Positive Breast Cancer
(Pharmacy, 2024 , Master Thesis)
HER-2 positive is a subtype of breast cancer that acquires poor prognosis and low survival rates. Targeted therapy is one of the main approaches that are used for the treatment of HER-2-positive breast cancer. However, it ...
INVESTIGATING THE ROLE OF THE ARYL HYDROCARBON RECEPTOR AND BCL-2 FAMILY PROTEINS IN OVARIAN CANCER STEM CELLS DEVELOPMENT AND CHEMORESISTANCE
(Pharmacy, 2024 , Dissertation)
Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC),
the most lethal gynecological malignancy, is clinically presented with chemoresistance
and a higher relapse rate. This could be endorsed ...
Development of A Novel Liposomal Formulation of a Pyridine Chalcone Analogue for HER-2 Positive Breast Cancer
(Pharmacy, 2024 , Master Thesis)
Breast cancer is the most prevalent cancer in women and the fifth leading cause of death due to cancer worldwide. Human epidermal growth factor receptor-2 (HER-2) is an oncoprotein that is overexpressed in 25-30% of breast ...
Nano Liposomal Formulation for A Novel Chalcone Compound as A Potential Anticancer Delivery System for Triple-Negative Breast Cancer
(Pharmacy, 2024 , Master Thesis)
Triple negative breast cancer is the most aggressive type of breast malignancy accounting for 15-20% of all breast cancer cases. Treatment of TNBC remains limited, with a high risk of relapse and metastasis to other organs. ...
APPLICATION OF SOLID DISPERSION IN CONJUNCTION WITH 3D PRINTING FOR PERSONALIZED MEDICINE
(Pharmacy, 2024 , Master Thesis)
Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ...
COST-EFFECTIVENESS ANALYSIS OF SUBCUTANEOUS DARATUMUMAB VERSUS INTRAVENOUS DARATUMUMAB IN NEWLY DIAGNOSED MULTIPLE MYELOMA
(Pharmacy, 2024 , Master Thesis)
Background: Both subcutaneous (SC) and intravenous (IV) formulations of Daratumumab (Dara) are used, in combination with lenalidomide, bortezomib, and dexamethasone (VRd), for treating newly diagnosed multiple myeloma ...
THE EFFECT OF OBESITY ON RIVAROXABAN PHARMACOKINETICS AND PHARMACODYNAMICS
(Pharmacy, 2024 , Dissertation)
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ...
CURCUMIN-CONJUGATED CHITOSAN OLIGOMERS DERIVED FROM MICROWAVE IRRADIATION FOR NANOFORMULATION IN COLON CANCER TREATMENT
(Pharmacy, 2024 , Master Thesis)
Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ...