Triple negative breast cancer is the most aggressive type of breast malignancy accounting for 15-20% of all breast cancer cases. Treatment of TNBC remains limited, with a high risk of relapse and metastasis to other organs. ...

HER-2 positive is a subtype of breast cancer that acquires poor prognosis and low survival rates. Targeted therapy is one of the main approaches that are used for the treatment of HER-2-positive breast cancer. However, it ...

Background: Primary care is an integral part of the healthcare system. Patients have better accessibility and continuity of care. However, studies have reported low-quality warfarin management in these settings. Pharmacist-led ...

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ...

Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. This could be endorsed ...

Objective: To summarize the literature evidence towards the efficacy and safety of diabetic neuropathy (DNP) treatments, and to assess the cost-effectiveness among the DNP treatment regimens in Qatar, including the use of ...

Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ...

Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ...

Background: Both subcutaneous (SC) and intravenous (IV) formulations of Daratumumab (Dara) are used, in combination with lenalidomide, bortezomib, and dexamethasone (VRd), for treating newly diagnosed multiple myeloma ...

Breast cancer is the most prevalent cancer in women and the fifth leading cause of death due to cancer worldwide. Human epidermal growth factor receptor-2 (HER-2) is an oncoprotein that is overexpressed in 25-30% of breast ...