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PRODUCTION OF LETROZOLE-LOADED MONODISPERSE POLYMERIC-BASED MICROPARTICLES FOR BREAST CANCER THERAPY
(Pharmacy, 2017 , Master Thesis)
Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. However, due to its adverse effects this study was designed to investigate the feasibility of producing ...
Relationship between the Stages of Change and Medication Adherence in Patients with Type 2 Diabetes Mellitus in a Primary Health Care Setting in Qatar
(Pharmacy, 2016 , Master Thesis)
Background: Non-adherence to medications is a major concern among patients with type 2 diabetes mellitus (T2DM). Failure to achieve positive health-related outcomes could be associated with non-adherence. Medication ...
SYNTHESIS, CHARACTERIZATION AND CYTOCOMPATIBILITY OF HIGHLY POROUS, THREE DIMENSIONAL POLY (1, 10 DECANEDIOL CO-TRICARBALLYLATE) BASED SCAFFOLDS FOR CARDIAC & OTHER TISSUE ENGINEERING APPLICATIONS
(Pharmacy, 2016 , Master Thesis)
Electrospinning is one of the recently developed methods that produces scaffolds resembling the natural extracellular matrix. It can utilize a wide array of natural and synthetic polymer materials to produce three dimensional, ...
PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
(Pharmacy, 2017 , Master Thesis)
Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ...
Medication-Related Burden among Patients with Chronic Disease Conditions: Perspectives of Patients attending Non-Communicable Disease Clinics in a Primary Healthcare Setting in Qatar
(Pharmacy, 2017 , Master Thesis)
This study aimed to adapt a medication-related burden instrument, the Living with Medicines Questionnaire (LMQ), into the Arabic context, report the psychometric properties of the Arabic version, and assess the burden ...
Barriers to medication adherence in patients with uncontrolled diabetes in a primary healthcare setting in Qatar: a mixed method triangulation study
(Pharmacy, 2017 , Master Thesis)
Background: In Qatar, 86% of patients with diabetes are uncontrolled. Given that nonadherence to oral drug therapy and psychological insulin resistance are a common phenomenon, one could postulate that patients may not be ...
Cost-effectiveness analysis of sedatives in the management of neonates undergoing mechanical ventilation in the intensive care setting in Qatar
(Pharmacy, 2017 , Master Thesis)
Background. Neonates with respiratory distress syndrome (RDS), admitted to the neonatal intensive care unit (NICU) at the Women’s Hospital (WH) in Qatar, often require mechanical ventilation (MV) to maintain ventilator ...
EVALUATION OF A CUMULATIVE EXIT-FROM-DEGREE OBJECTIVE STRUCTURED CLINICAL EXAMINATION (OSCE) IN A GULF CONTEXT
(Pharmacy, 2016 , Master Thesis)
This study aimed to evaluate the psychometric properties of the 2nd iteration of an Objective Structured Clinical Examination (OSCE) for graduating pharmacy students in Qatar. A secondary objective of this study was to ...
Cathepsin B Induced Cardiomyocyte Hypertrophy Requires Activation of The Na+/H+ Exchanger Isoform-1
(Pharmacy, 2016 , Master Thesis)
Multiple studies have demonstrated that proteases, specifically cathepsin B (Cat B) and matrix metalloproteinase-9 (MMP-9) contribute to the remodeling of the extracellular matrix (ECM), a hallmark of cardiac hypertrophy ...
THE EFFECT OF GENETIC AND NON-GENETIC FACTORS ON WARFARIN DOSE VARIABILITY IN QATARI POPULATION
(Pharmacy, 2018 , Master Thesis)
Introduction: Genetic and non-genetic factors were shown to affect warfarin dosing; however, their effect may vary from one population to the other. No previous studies were conducted on the Qatari population to elucidate ...