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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(Pharmacy, 2021 , Master Thesis)
Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ...
ASSESSMENT OF ADHERENCE, BARRIERS AND STRENGTHS TO ADHERENCE AMONG ADOLESCENTS WITH TYPE 1 DIABETES IN QATAR: PERSPECTIVES OF PATIENTS AND THEIR CAREGIVERS
(Pharmacy, 2021 , Master Thesis)
Background: Metabolic control among adolescents with type 1 diabetes mellitus (T1DM) is generally poor. Non-adherence is one of the contributors to this poor glycemic control, leading to high complication rates. The objective ...
COMMUNITY PHARMACISTS' SELF-PERCEIVED COMPETENCY, AND ENABLERS, AND BARRIERS TOWARDS THE MANAGEMENT OF COMMON MINOR AILMENTS IN QATAR
(Pharmacy, 2021 , Master Thesis)
The study aimed to assess community pharmacists' self-perceived competency, and enablers and barriers towards managing common minor ailments in Qatar, and its predictors. A cross-sectional study, with pretested questionnaires, ...
Multi-Criteria Decision Analytic Model for the Comparative Formulary Inclusion of Direct Oral Anticoagulant in Qatar
(Pharmacy, 2020 , Master Thesis)
Aim: The formulary inclusion of direct oral anticoagulant (DOACs) in the government
hospital health services in Qatar is not comparative or restricted. Requests to include a
DOAC in the formulary are typically accepted ...
MODULATION OF THE MOLECULAR EXPRESSION AND FUNCTION OF BCL-2 FAMILY PROTEINS BY THE ARYL HYDROCARBON RECEPTOR IN BREAST CANCER STEM CELLS OF THE MDA-MB-231
(Pharmacy, 2021 , Master Thesis)
Breast cancer (BC) is a frequently occurring neoplasm in women and is a second major cause of cancer related deaths. Despite the remarkable advancements in the understanding of BC and its treatments, the diseases still ...
Surface Coating of Carbon Nanofiber by Mesoporous Silica: a Promising Strategy to Reduce its Toxicity during Embryogenesis
(Pharmacy, 2021 , Master Thesis)
Although carbon nanofibers (CNFs) have been implicated in biomedical
applications, they are still considered as a potential hazard. Conversely, mesoporous
silica nanoparticles are generally considered as a suitable and ...
Strengthening the Quality of Clinical Pharmacokinetic Studies: Development and Validation of a Critical Appraisal Tool For Clinical Pharmacokinetic Research
(Pharmacy, 2020 , Master Thesis)
Background: Critical appraisal process is central to the practice of evidence-based
medicine that aids in assessing the quality of the published scientific knowledge. To
our knowledge, there is no critical appraisal ...
Sleep Patterns among University Students and Insomnia Management in Primary Care Settings in Qatar: A Two-Phase Investigation
(Pharmacy, 2020 , Master Thesis)
Insomnia is a public health concern that affects approximately a third of adult
population worldwide. The aim of this research was to investigate insomnia and its
management among university students and primary care ...
Clinical And Pharmacokinetic Evaluation Of Optimal Monitoring Parameters And Sampling Schemes For Vancomycin Therapeutic Drug Monitoring In Qatar
(Pharmacy, 2018 , Master Thesis)
Background: Therapeutic drug monitoring (TDM) of vancomycin has been
proven to maximize therapeutic outcomes and minimize toxicity when
conducted appropriately. The quality of vancomycin TDM services in many
settings ...
Evaluation of the Pharmacovigilance System in Qatar: A Mixed Method Study on Structure Process, And Outcome
(Pharmacy, 2020 , Master Thesis)
Introduction: It is evident that pharmacovigilance (PV) centers are the
entities required to ensure medication safety and protect public health from drug
related morbidity and mortality. In many developing countries PV ...