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THE EFFECT OF GENETIC AND NON-GENETIC FACTORS ON WARFARIN DOSE VARIABILITY IN QATARI POPULATION
(Pharmacy, 2018 , Master Thesis)
Introduction: Genetic and non-genetic factors were shown to affect warfarin dosing; however, their effect may vary from one population to the other. No previous studies were conducted on the Qatari population to elucidate ...
Exploring Healthcare Provider Perceptions Of Narcotic Use Related To Cancer Pain Treatment In Qatar
(Pharmacy, 2018 , Master Thesis)
Purpose: The aim of this thesis to explore narcotic use for cancer patients in Qatar from health professional perspectives, in order to further understand facilitators and barriers for optimal prescribing, including any ...
Pharmacoeconomics Evaluation of the Systemic Antifungal Posaconazole for Prophylaxis against Invasive Fungal Infections among Immunocompromised Cancer Patients in Qatar
(Pharmacy, 2018 , Master Thesis)
The immunocompromised hematologic malignancy patients, at the National Center
for Cancer Care (NCCCR) in Qatar, receive the antifungal posaconazole for prophylaxis
as systemic prophylaxis against invasive fungal infections ...
THE ROLE OF P90 RIBOSOMAL S6 KINASE AND AUTOPHAGY IN SUNITINIB AND PONATINIB-INDUCED CARDIOTOXICITY
(Pharmacy, 2019 , Master Thesis)
In recent years, the paradigm cancer management has shifted towards a targeted approach. Among the newly targeted anticancer therapies are ponatinib and sunitinib, small molecules tyrosine kinase inhibitors (TKIs), used ...
Clinical and Economic Evaluation of Surfactant Use in the Management of Meconium Aspiration Syndrome in the Intensive: Care Setting In Qatar
(Pharmacy, 2020 , Master Thesis)
Background. Surfactant replacement therapy is widely used in the management of the
life-threatening condition of Meconium Aspiration Syndrome (MAS), with no clear
guidance on its best use. This thesis constitutes two ...
Evaluating Pharmacy Health Literacy and Its Barriers among Patients with Cardiovascular Diseases in Qatar
(Pharmacy, 2020 , Master Thesis)
Background: Patients’ health literacy, which is their capacity to obtain, process, and understand
basic health information and services needed to make appropriate health decisions, is a critical
determinant of whether ...
Evaluation of the Pharmacovigilance System in Qatar: A Mixed Method Study on Structure Process, And Outcome
(Pharmacy, 2020 , Master Thesis)
Introduction: It is evident that pharmacovigilance (PV) centers are the
entities required to ensure medication safety and protect public health from drug
related morbidity and mortality. In many developing countries PV ...
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
(Pharmacy, 2020 , Master Thesis)
Poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery
systems and gene transfection as drug carriers. They also exert several biological effects
including modulating gene expression and interfering with ...
Strengthening the Quality of Clinical Pharmacokinetic Studies: Development and Validation of a Critical Appraisal Tool For Clinical Pharmacokinetic Research
(Pharmacy, 2020 , Master Thesis)
Background: Critical appraisal process is central to the practice of evidence-based
medicine that aids in assessing the quality of the published scientific knowledge. To
our knowledge, there is no critical appraisal ...
Economic Evaluation of the Cyp2c19 Genotype-Guided Antiplatelet Therapy Compared To Universal Use of Ticagrelor or Clopidogrel in Qatar
(Pharmacy, 2020 , Master Thesis)
Background: Clopidogrel requires activation primarily by cytochrome P450 2C19
(CYP2C19). Patients with CYP2C19 loss-of-function alleles (LOF) are at increased risk
of major adverse cardiovascular events. Ticagrelor is ...