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AuthorJoshy K.S.
AuthorAugustine R.
AuthorLi T.
AuthorSnigdha S.
AuthorHasan, Anwarul
AuthorKomalan C.
AuthorKalarikkal N.
AuthorThomas S.
Available date2022-05-21T10:18:30Z
Publication Date2020
Publication NameInternational Journal of Biological Macromolecules
ResourceScopus
Identifierhttp://dx.doi.org/10.1016/j.ijbiomac.2020.04.175
URIhttp://hdl.handle.net/10576/31299
AbstractCurcumin loaded lipid-polymer hybrid nanoparticles dispersions were fabricated from carboxymethylcellulose, stearic acid, polyethylene glycol and sesame oil using emulsion solvent evaporation method for their possible application as edible coatings for fresh vegetables and fruits. They were characterized by FTIR and TEM analysis. In addition, anti-bacterial, blood compatibility, cytotoxicity and anticancer studies were also carried out. The prepared nanodispersions showed excellent mixed nanostructured morphology with an average size of 94.96 nm. The hybrid nanodispersions showed excellent blood compatibility, non-toxicity and antitumor activity. The synthesized nanoparticle dispersion was employed as an edible coating solution for fresh apples and tomatoes. The hybrid system coated vegetables and fruits shows minimal weight loss after 15 days of storage. Hence, the formulated hybrid nanostructures of CMC are promising as edible coating solution, in addition to possessing the properties to fight cancer.
Languageen
PublisherElsevier B.V.
SubjectAnti-cancer activity
Carboxymethylcellulose
Curcumin, drug delivery
Edible coating
TitleCarboxymethylcellulose hybrid nanodispersions for edible coatings with potential anti-cancer properties
TypeArticle
Volume Number157
dc.accessType Abstract Only


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