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AuthorLi, Xiaolong
AuthorYang, Xuanyu
AuthorCheng, Xiaowei
AuthorZhao, Yuye
AuthorLuo, Wei
AuthorElzatahry, Ahmed A.
AuthorAlghamdi, Abdulaziz
AuthorHe, Xing
AuthorYang, Xuanyu
AuthorSu, Jiacan
AuthorDeng, Yonghui
Available date2022-05-22T09:12:24Z
Publication Date2020
Publication NameJournal of Colloid and Interface Science
ResourceScopus
Identifierhttp://dx.doi.org/10.1016/j.jcis.2020.02.118
URIhttp://hdl.handle.net/10576/31362
AbstractIn past decade, Pt-based nanomaterials as peroxidase mimics have attracted much attention for H2O2 and glucose detection. However, easy aggregation of Pt nanoparticles (Pt NPs) greatly decreases their peroxidase-like activity. In this work, novel Pt/EMT nanocomposites were prepared by uniformly loading Pt NPs (5?8 nm) onto the support of ultrasmall EMT zeolite (15?20 nm), a kind of low-silica microporous aluminosilicate material. The hybrid Pt/EMT nanomaterials could be well dispersed in water to form a homogeneous suspension, and were then utilized as a superior peroxidase-like catalyst for oxidation of 3,3?,5,5?-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). The optimal catalyst of 2.6Pt/EMT nanocomposite exhibited excellent catalytic performance toward H2O2 and TMB than natural enzyme of horseradish peroxidase (HRP) by using a steady-state kinetic analysis based on the typical Michaelis-Menten kinetics theory. The peroxidase-like catalyst showed a promising activity in a wide pH and temperature range as well as the long-term stability. A facile and reliable colorimetric assay based on the peroxidase mimic of Pt/EMT nanocomposite was constructed for precise detection of H2O2 and glucose in a wide linear range, with low limits of detection of 1.1 ?M and 13.2 ?M, respectively. Due to high selectivity to glucose against other sugars on the catalyst, the method was demonstrated to accurately measure the concentration of glucose in real samples including human blood serum and fruit juices, indicating a potential application of the Pt/EMT nanocomposites as a robust peroxidase mimic and a reliable biosensor in the fields of clinical diagnosis, pharmaceutical, food research and so on. 2020
Languageen
PublisherElsevier Inc.
SubjectCatalyst activity
Catalyst selectivity
Clinical research
Colorimetry
Diagnosis
Fruit juices
Glucose
Metal nanoparticles
Nanocomposites
Platinum
Silica
Zeolites
Colorimetric assays
Glucose detection
Homogeneous suspensions
Low limits of detections
Michaelis-Menten kinetic
Microporous aluminosilicates
Peroxidase mimics
Peroxidase-like activities
Platinum compounds
glucose
horseradish peroxidase
hydrogen peroxide
nanocomposite
peroxidase
platinum nanoparticle
zeolite
glucose
hydrogen peroxide
metal nanoparticle
platinum
zeolite
adsorption
Article
colorimetry
desorption
fruit juice
glucose assay
human
limit of detection
maximum reaction velocity
Michaelis Menten kinetics
nonhuman
oxidation
particle size
pH
priority journal
surface area
temperature
transmission electron microscopy
X ray photoemission spectroscopy
X ray powder diffraction
chemistry
fruit and vegetable juice
surface property
Fruit and Vegetable Juices
Glucose
Humans
Hydrogen Peroxide
Metal Nanoparticles
Particle Size
Platinum
Surface Properties
Zeolites
TitleHighly dispersed Pt nanoparticles on ultrasmall EMT zeolite: A peroxidase-mimic nanoenzyme for detection of H2O2 or glucose
TypeArticle
Pagination300-311
Volume Number570


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