Browsing Medicine Research by Title
Now showing items 290-309 of 758
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F-box proteins in cancer stemness: An emerging prognostic and therapeutic target
( Elsevier , 2021 , Article)Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ... -
Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets
( American Society for Clinical Investigation , 2019 , Article)Tumor-infiltrating lymphocytes (TILs) are widely associated with positive outcomes, yet carry key indicators of a systemic failed immune response against unresolved cancer. Cancer immunotherapies can reverse their tolerance ... -
Fascin in Gynecological Cancers: An Update of the Literature
( MDPI , 2021 , Article)Fascin is an actin-binding protein that is encoded by the gene (located on chromosome 7). It triggers membrane projections and stimulates cell motility in cancer cells. Fascin overexpression has been described in different ... -
Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target
( Oxford University Press , 2019 , Article Review)In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ... -
First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report
( Elsevier Ltd , 2019 , Article)Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is ... -
Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis
( Taylor and Francis Ltd , 2018 , Article)Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ... -
Follicular dendritic cells
( Wiley , 2021 , Article Review)Follicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, ... -
Forensic utility of cranial measurements in stature reconstruction in South Africans of European descent.
( E Schweizerbart Science Publishers , 2020 , Article)The height of an individual (stature) is one of the biological profiles that is estimated as part of human identification process from various components of the human skeleton. The anatomical method is often used for this ... -
A free terminal ileal perforation as the presenting sign of crohn’s disease in an adolescent female
( University Clinical Hospital Tuzla , 2020 , Article)The authors present a rare case of Aa free terminal ileal perforation as the presenting sign of Crohn's disease in an adolescent female. -
The Freeman–Tukey double arcsine transformation for the meta-analysis of proportions: Recent criticisms were seriously misleading
( John Wiley & Sons, Ltd , 2021 , Other)Pooling of proportions in meta-analysis are used to get better and more precise estimates of disease frequency, including cumulative incidence or prevalence. Meta-analysis is of course only useful when there are a limited ... -
Frequency of adjustment with comorbidity and illness severity scores and indices in cardiac arrest research
( Elsevier , 2017 , Article)Background Previous research demonstrates that results from observational research correlate well with results from clinical trials, and if the former are well designed these can guide clinical practice. Observational ... -
Frequency of Parathyroid Hormone Assessment in the Evaluation of Hypercalcemia. A Comparison Between Patients With and Without a History of Malignancy in a 20-year Dataset of 20,954 Patients
( SAGE Publications Ltd , 2021 , Article)Background: The purpose of this study was to evaluate whether a prior diagnosis of malignancy affected the assessment of parathyroid hormone (PTH) in hypercalcemic patients and whether the rate of this assessment changed ... -
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
( Wiley , 2020 , Article)© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ... -
G protein estrogen receptor as a potential therapeutic target in Raynaud’s phenomenon
( Frontiers Media , 2022 , Article)Exaggerated cold-induced vasoconstriction can precipitate a pathogenesis called Raynaud’s phenomenon (RP). Interestingly, RP is significantly more prevalent in females than age-matched men, highlighting the potential ... -
Gallbladder cancer: 7-Year experience from Qatar
( Elsevier Ltd , 2019 , Article)Thirty-five patients presented with GC during the study period, 10 females (28.6%) and 25 males (71.4%). Fourteen patients (40%) were diagnosed incidentally after laparoscopic cholecystectomy, 16 (48.6%) were diagnosed ... -
Gastric Necrosis and Perforation Following Massive Gastric Dilatation in an Adolescent Girl: A Rare Cause of Acute Abdomen.
( Frontiers Media , 2019 , Article)Gastric necrosis with perforation is a rare and potentially life-threatening condition in childhood beyond the neonatal period. We report a case of gastric necrosis and perforation of a portion of the great curvature due ... -
Gene expression and miRNAs profiling: Function and regulation in human epidermal growth factor receptor 2 (HER2) - positive breast cancer
( MDPI AG , 2019 , Article)Breast cancer is the second most common cause of cancer-related deaths among women worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the subtypes, human epidermal growth factor receptor 2 ... -
Generalisability theory analyses of concept mapping assessment scores in a problem-based medical curriculum
( Blackwell Publishing Ltd , 2016 , Article)Context In problem-based learning (PBL), students construct concept maps that integrate different concepts related to the PBL case and are guided by the learning needs generated in small-group tutorials. Although an ... -
A generalized pairwise modelling framework for network meta-analysis.
( Lippincott, Williams & Wilkins , 2018 , Article)Indirect comparison methods are used to measure the effect of two treatments that were each compared against a similar control group in a meta-analysis. The network meta-analysis method extends this to multiple treatments ... -
Genetic risk factors in melanoma etiopathogenesis and the role of genetic counseling: A concise review.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2022 , Article Review)Melanoma is a highly aggressive cancer originating from melanocytes. Its etiopathogenesis is strongly related to genetic, epigenetic, and environmental factors. Melanomas encountered in clinical practice are predominantly ...
