Browsing Medicine Research by Title
Now showing items 414-433 of 758
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L5 Spinal Nerve Axotomy Induces Distinct Electrophysiological Changes in Axotomized L5- and Adjacent L4-Dorsal Root Ganglion Neurons in Rats .
( Mary Ann Liebert , 2020 , Article)Peripheral neuropathic pain (PNP) is a major health problem for which effective drug treatment is lacking. Its underlying neuronal mechanisms are still illusive, but pre-clinical studies using animal models of PNP including ... -
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic.
( BMC , 2020 , Article)Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ... -
Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy
( Karger , 2019 , Article)We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma (GN) during the diagnostic work up of alopecia areata (AA). Clinical Presentation and Intervention Laboratory investigations revealed ... -
Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
( BMC , 2020 , Article)© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ... -
Large expanding splenic pseudocyst: A case report and review of literature
( Elsevier , 2021 , Article)Introduction and importance Splenic pseudocysts are extremely uncommon. Most of these cysts are asymptomatic and may result from previous blunt abdominal trauma. We report an interesting uncommon case of large splenic ... -
Large uterine juvenile cystic adenomyoma in an adolescent
( Elsevier , 2022 , Article)Juvenile cystic adenomyoma (JCA) is a rare uterine pathology with <40 cases reported in the current literature since 1996 when Tamura described it. We report a 13-year-old girl with a history of chronic pelvic pain and ... -
A large, highly vascularized sacrococcygeal teratoma in a preterm male infant: A case report.
( Elsevier , 2021 , Article)Sacrococcygeal teratoma (SCT) is a rare tumor with an incidence of 1:35.000/40.000 live births. SCTs are composed of both cystic and solid components. Predominantly cystic SCTs are more likely to be benign and have a better ... -
Lecturing skills as predictors of tutoring skills in a problem-based medical curriculum
( Dove Press , 2016 , Article)Purpose: Recruitment of tutors to work in problem-based learning (PBL) programs is challenging, especially in that most of them are graduated from discipline-based programs. Therefore, this study aims at examining whether ... -
Letter re: stratification by quality is not recommended in meta-analysis.
( Elsevier , 2019 , Other)None -
Letter to editor/comment
( Blackwell Publishing Inc. , 2019 , Other)[No abstract available] -
Letter to editor/comment : Metaplastic carcinoma of the breast: Prognosis and response to systemic treatment in metastatic disease
( Wiley , 2019 , Other)Comment on the recent paper on metaplastic breast carcinoma study published in the Breast Journal 2019. -
Letter to Editor: Apocrine carcinoma is the fact. Comment on the recent paper entitled "Invasive apocrine carcinoma of the breast: Myth or fact?" by Gurrado et al (Breast J. 2019 Sep 8. doi: 10.1111/tbj.13569. [Epub ahead of print].
( Wiley , 2019 , Article)The most recent WHO classification of breast cancer also recognizes the concept of “pure apocrine carcinoma” (called carcinoma with apocrine differentiation) with cancers having >90% of apocrine morphology (an essential ... -
Letter to the Editor/Response
( Blackwell Publishing Inc. , 2019 , Article)[No abstract available] -
Lichen planus: a comprehensive evidence-based analysis of medical treatment
( Blackwell Publishing Ltd , 2019 , Article Review)Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ... -
Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket
( Elsevier , 2023 , Article)Calmodulin (CaM) modulates the activity of several proteins that play a key role in excitation-contraction coupling (ECC). In cardiac muscle, the major binding partner of CaM is the type-2 ryanodine receptor (RyR2) and ... -
Likelihood ratio interpretation of the relative risk
( BMJ Publishing Group , 2022 , Article)Interpreting diagnostic test results in medicine The likelihood ratio (LR) is today commonly used in medicine for diagnostic inference. Historically, it was preceded by introduction, in 1966, of the predictive value ... -
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet.
( BMC , 2020 , Article)Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates ... -
Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery
( Acta Materialia Inc , 2019 , Article)In the present study, a novel biodegradable Zn-0.8Cu coronary artery stent was fabricated and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed that the implanted stent was able to ... -
Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes
( Elsevier Ltd , 2019 , Article)Background To evaluate effectiveness, safety, and costs of Lorcaserin vs. phentermine among obese non–surgical and surgical patients (post bariatric surgery). Methods This retrospective study retrieved charts of all ... -
A low glycemic diet protects disease-prone Nrf2-deficient mice against age-related macular degeneration.
( Elsevier , 2020 , Article)Age-related macular degeneration (AMD) is a major blinding disease, affecting over 14% of the elderly. Risk for AMD is related to age, diet, environment, and genetics. Dietary modulation of AMD risk is a promising treatment ...
