Browsing Medicine Research by Title

Now showing items 986-1005 of 1255

    • Racing for COVID-19 Vaccine and Cure: Lessons and Tragedies in Human Subject Research. 

      Salam, Amar M; Carr, Alison S ( Medknow Publications , 2020 , Article)
      Pressured by the enormous human and economic costs of the COVID-19 pandemic, certain countries and political figures have advocated the use of drugs and vaccines that did not go through the required regulatory stages of ...

    • Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy 

      Yi F.; Hou W.; Zhou C.; Yin Y.; Lu S.; ... more authors ( NLM (Medline) , 2019 , Article)
      BACKGROUND: Radiofrequency ablation (RFA) and antiarrhythmic drugs (AADs) are the main treatments used for atrial fibrillation (AF). In recent years, a number of articles comparing the 2 treatments have begun to emerge. ...

    • RamanNet: a generalized neural network architecture for Raman spectrum analysis 

      Ibtehaz, Nabil; Chowdhury, Muhammad E. H.; Khandakar, Amith; Kiranyaz, Serkan; Rahman, M. Sohel; ... more authors ( Springer Science and Business Media Deutschland GmbH , 2023 , Article)
      Raman spectroscopy provides a vibrational profile of the molecules and thus can be used to uniquely identify different kinds of materials. This sort of molecule fingerprinting has thus led to the widespread application of ...

    • Randomized clinical trial comparing abluminal biodegradable polymer sirolimus-eluting stents with durable polymer sirolimus-eluting stents: Nine months angiographic and 5-year clinical outcomes 

      Zhang, Haijun; Wang, Xiangfei; Deng, Wei; Wang, Shenguo; Ge, Junbo; ... more authors ( Wolters Kluwer Health, Inc , 2016 , Article)
      Background: The biodegradable polymer drug-eluting stents (DES) were developed to improve vascular healing. However, further data and longer-term follow-up are needed to confirm safety and efficacy of these stents. This ...

    • Rapid detection of bacterial infections using nanotechnology-based point-of-care sensor with Raman spectroscopy 

      Zughaier, Susu; Wu, Xiaomeng; Chen, Jen; Zhao, Yiping ( Hamad bin Khalifa University Press (HBKU Press) , 2020 , Article)
      Background: Mass gathering is a risk factor for infectious diseases transmission. Therefore, rapid detection of infections is highly desirable. The current gold standard approach to detect bacterial infections in clinical ...

    • Rapid evidence synthesis approach for limits on the search date: how rapid could it be? 

      Xu, Chang; Ju, Ke; Lin, Lifeng; Jia, Pengli; Kwong, Joey S W; ... more authors ( John Wiley and Sons , 2021 , Article)
      Rapid reviews have been widely employed to support timely decision-making, and limiting the search date is the most popular approach in published rapid reviews. We assessed the accuracy and workload of search date limits ...

    • Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes 

      George, Hindy; Dornbos, Peter; Chaffin, Mark D.; Liu, Dajiang J.; Wang, Minxian; ... more authors ( Elsevier , 2022 , Article)
      Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele ...

    • Rare presentation of primary varicella zoster as fatal fulminant hepatitis in adult on low-dose,short-term steroid: Case report 

      Toffaha A.; El Ansari W.; Ramzee A.F.; Afana M.; Aljohary H. ( Elsevier Ltd , 2019 , Article)
      Background Varicella zoster virus presents clinically as primary (chickenpox) or secondary (herpes zoster) infection. Cutaneous and extracutaneous dissemination may occur, usually in immunocompromised patients. VZV ...

    • A Rare Sequela of Constriction Band Syndrome: Case Report. 

      Al Basti, Habib; Ahmed, Mohamed Badie; Sada, Ruba; Malki, Mohammed Imad; Al Lahham, Salim ( Lippincott, Williams & Wilkins , 2021 , Report)
      The patient in this case report is a 19-year-old man who presented with left foot cauliflower lesion. He complained of an inability to wear proper shoes, in addition to an unpleasant appearance of his foot. The lesion was ...

    • Reactive oxygen species: Modulators of phenotypic switch of vascular smooth muscle cells 

      Badran, Adnan; Nasser, Suzanne A.; Mesmar, Joelle; El-Yazbi, Ahmed F.; Bitto, Alessandra; ... more authors ( MDPI , 2020 , Article Review)
      Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling. However, high ROS levels cause oxidative stress, which is implicated ...

    • Reading patterns of proteome damage by glycation, oxidation and nitration: quantitation by stable isotopic dilution analysis LC-MS/M 

      Rabbani, Naila; Thornalley, Paul J. ( Portland Press , 2020 , Article Review)
      Liquid chromatography-tandem mass spectrometry (LC-MS/MS) provides a high sensitivity, high specificity multiplexed method for concurrent detection of adducts formed by protein glycation, oxidation and nitration, also ...

    • Real-World Effectiveness of the Varicella Vaccine among Children and Adolescents in Qatar: A Case–Control Study 

      Bibi, Zahra; Nawaz, Ahmed Daniyal; Al Kurbi, Maha; Fakhroo, Shahad; Ferih, Khaled; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Background: Despite the availability of a highly efficacious vaccine, varicella outbreaks are still being reported globally. In this study, we evaluated the real-world effectiveness of varicella vaccination among children ...

    • Recent advances in nanotherapeutics for multiple myeloma 

      Iannazzo, Daniela; Ettari, Roberta; Giofrè, Salvatore; Eid, Ali H.; Bitto, Alessandra ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)
      Anticancer therapies cannot be included in a one-size-fits-all scenario; it is imperative to adapt therapies to the tumor molecular profile and most importantly to develop target-specific therapeutics. Nanotherapeutics can ...

    • Redefining effect modification 

      Doi, Suhail A.; Abdulmajeed, Jazeel; Xu, Chang ( Wiley , 2022 , Article)
      The odds ratio (OR) has been misunderstood in evidence based medicine and clinical epidemiology. Currently, “noncollapsibility” is considered a problem with interpretation of the OR and it is thought that the OR is rarely ...

    • Reducing the number of rebooking of urgent in-person visits in general paediatric ambulatory clinics during the COVID-19 pandemic 

      Hassan, Manasik; Abdalla, Tasneim; Magboul, Samar; Dafallah, Musa; Mohamed, Tasabeh; ... more authors ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)
      Background: Due to the COVID-19 pandemic, all out-patients clinics shifted to telehealth visits 1 . However some patients still needed to be seen as face to face visit 2 , mostly through the new urgent referrals which were ...

    • Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production 

      Galal, Youssef; Zaravinos, Apostolos; Bonavida, Benjamin ( Elsevier , 2021 , Book chapter)
      RKIP (Raf kinase inhibitory protein) is a metastatic suppressor and a chemo-immuno-sensitizer. The deficiency or loss of RKIP has been linked with different cancer types, resulting in the activation of the MAPK pathway, ...

    • Regulatory enforcement of the marketing of fixed-dose combinations in India: a case study of systemic antibiotics 

      Brhlikova, Petra; Mehta, Aashna; McGettigan, Patricia; Pollock, Allyson M.; Roderick, Peter; ... more authors ( Springer Nature , 2023 , Article)
      Background: In India, states have licensed the manufacture of large numbers of fixed-dose combination (FDC) drugs without the required prior approval of the central regulator. This paper describes two major regulatory ...

    • Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes 

      Burgon, Patrick G.; Weldrick, Jonathan J.; Talab, Omar Mohamed Sayed Ahmed; Nadeer, Muhammad; Nomikos, Michail; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Heart disease remains a global leading cause of death and disability, necessitating a comprehensive understanding of the heart’s development, repair, and dysfunction. This review surveys recent discoveries that explore the ...

    • Reinforcement learning-based control of tumor growth under anti-angiogenic therapy. 

      Yazdjerdi, Parisa; Meskin, Nader; Al-Naemi, Mohammad; Al Moustafa, Ala-Eddin; Kovács, Levente ( Elsevier , 2019 , Article)
      In recent decades, cancer has become one of the most fatal and destructive diseases which is threatening humans life. Accordingly, different types of cancer treatment are studied with the main aim to have the best treatment ...

    • The Relationship between Changes in MYBPC3 Single-Nucleotide Polymorphism-Associated Metabolites and Elite Athletes’ Adaptive Cardiac Function 

      Riguene, Emna; Theodoridou, Maria; Barrak, Laila; Elrayess, Mohamed A.; Nomikos, Michail ( MDPI , 2023 , Article Review)
      Athletic performance is a multifactorial trait influenced by a complex interaction of environmental and genetic factors. Over the last decades, understanding and improving elite athletes’ endurance and performance has ...