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Chronic administration of nano-sized PAMAM dendrimers in vivo inhibits EGFR-ERK1/2-ROCK signaling pathway and attenuates diabetes-induced vascular remodeling and dysfunction.
(
Elsevier
, 2019 , Article)
We investigated whether chronic administration of nano-sized polyamidoamine (PAMAM) dendrimers can have beneficial effects on diabetes-induced vascular dysfunction by inhibiting the epidermal growth factor receptor ...
An interdisciplinary specialist team leads to improved diagnostics and treatment for paediatric patients with vascular anomalies
(
John Wiley & Sons Ltd.
, 2015 , Article)
Aim Patients with vascular anomalies are often misdiagnosed, leading to delayed or improper treatment. The aim of this study was to evaluate the impact of an interdisciplinary team on the diagnosis and treatment of ...
Identifying essential competencies for medical students
(
Emerald Group Publishing Ltd.
, 2019 , Article)
Purpose
The purpose of this paper is to identify essential profession-related competencies, clinical knowledge and skills that medical students should develop in the early stages of their education for future professional ...
Neuropathic itch
(
NLM (Medline)
, 2019 , Article)
Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their ...
The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.
(
Springer Nature
, 2020 , Article)
Kaufman oculocerebrofacial syndrome (KOS) is a severe autosomal recessive disorder characterized by intellectual disability, developmental delays, microcephaly, and characteristic dysmorphisms. Biallelic mutations of UBE3B, ...
Pertussis toxin IgA testing over-diagnoses recent pertussis infection
(
Elsevier
, 2017 , Article)
The importance of pertussis toxin (PT) IgA testing in the diagnosis of recent pertussis infection remains unclear. The contribution of PT IgA to the diagnosis of recent pertussis was reviewed in two separate analyses. ...
Meta-analysis of intracavitary electrocardiogram guidance for peripherally inserted central catheter placement
(
SAGE Publications Ltd
, 2019 , Article Review)
Background:
Recently, intracavitary electrocardiogram technology has been applied to peripherally inserted central catheter placement and demonstrates many potential advantages. However, the tip positioning accuracy of ...
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
(
Karger Publishers
, 2018 , Article)
The aim of this study was to identify differences in proteome profiles of diffuse large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the search for new markers and drug targets. Six DLBCL, with ...
Can atorvastatin with metformin change the natural history of prostate cancer as characterized by molecular, metabolomic, imaging and pathological variables? A randomized controlled trial protocol
(
Elsevier
, 2016 , Article)
Background Atorvastatin and metformin are known energy restricting mimetic agents that act synergistically to produce molecular and metabolic changes in advanced prostate cancer (PCa). This trial seeks to determine whether ...
Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis
(
Elsevier
, 2017 , Article)
Background Soil-transmitted helminth infections are a major global health issue, causing substantial morbidity in the world's poorest populations. Regular delivery of anthelmintic drugs is the mainstay for global ...