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Pertussis toxin IgA testing over-diagnoses recent pertussis infection
(
Elsevier
, 2017 , Article)
The importance of pertussis toxin (PT) IgA testing in the diagnosis of recent pertussis infection remains unclear. The contribution of PT IgA to the diagnosis of recent pertussis was reviewed in two separate analyses. ...
Can atorvastatin with metformin change the natural history of prostate cancer as characterized by molecular, metabolomic, imaging and pathological variables? A randomized controlled trial protocol
(
Elsevier
, 2016 , Article)
Background Atorvastatin and metformin are known energy restricting mimetic agents that act synergistically to produce molecular and metabolic changes in advanced prostate cancer (PCa). This trial seeks to determine whether ...
Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis
(
Elsevier
, 2017 , Article)
Background Soil-transmitted helminth infections are a major global health issue, causing substantial morbidity in the world's poorest populations. Regular delivery of anthelmintic drugs is the mainstay for global ...
Effect of Immediate Administration of Antibiotics in Patients With Sepsis in Tertiary Care: A Systematic Review and Meta-analysis
(
Elsevier
, 2017 , Article)
Purpose The goal of this review was to synthesize existing evidence regarding outcomes (mortality) for patients who present to the emergency department, are administered antibiotics immediately (within 1 hour) or later (>1 ...
Prostate biopsy, targeted prophylaxis and infectious complications: a critique of methods used
(
Wiley
, 2016 , Article)
Commentary
Nonphysician Out-of-Hospital Rapid Sequence Intubation Success and Adverse Events: A Systematic Review and Meta-Analysis
(
Elsevier
, 2017 , Article)
Study objective: Rapid sequence intubation performed by nonphysicians such as paramedics or nurses has become increasingly common in many countries; however, concerns have been stated in regard to the safe use and ...
Frequency of adjustment with comorbidity and illness severity scores and indices in cardiac arrest research
(
Elsevier
, 2017 , Article)
Background Previous research demonstrates that results from observational research correlate well with results from clinical trials, and if the former are well designed these can guide clinical practice. Observational ...
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
(
Elsevier
, 2021 , Article)
The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ...
Effectiveness of Market-Level Biosecurity at Reducing Exposure of Poultry and Humans to Avian Influenza: A Systematic Review and Meta-Analysis.
(
Oxford University Press
, 2018 , Article)
In this study, we aimed to identify the effect of market-level risk factors on avian influenza (AI) infection in poultry and humans and generate evidence that will inform AI prevention and control programs at live bird ...