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Now showing items 21-26 of 26
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
(
Taylor and Francis Ltd
, 2020 , Article)
Objectives: Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize ...
Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis
(
Taylor and Francis Ltd
, 2018 , Article)
Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ...
Research Methods for Zero Event Proportion Studies: The Incidence of Bleeding After Thoracentesis and Tube Thoracostomy in Patients With Uncorrected Coagulopathy
(
Elsevier Inc.
, 2021 , Article)
In a recent meta-analysis published in CHEST (November 2021), Fong et al1 investigated the incidence of bleeding after thoracentesis and tube thoracostomy in patients with uncorrected coagulopathy. The authors used the ...
Information on harm outcomes was insufficiently reported in systematic reviews and meta-analyses of individual participant data
(
John Wiley and Sons Inc
, 2021 , Other)
Meta-analysis is an important tool for summarizing findings from scientific research. But for harm outcomes,issues may arise due to the distribution problems, zero-events problems, as well as low statistical power. Individual ...
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis
(
American Society for Clinical Investigation
, 2022 , Article)
People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which ...
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
(
Elsevier
, 2023 , Article)
Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ...