Medicine Research: Recent submissions
Now showing items 1001-1020 of 1820
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Intake of Caffeine Containing Sugar Diet Remodels Gut Microbiota and Perturbs Drosophila melanogaster Immunity and Lifespan
( Elsevier , 2023 , Article)The diet-microbiome-immunity axis is one among the many arms that draw up the “we are what we intake” proclamation. As such, studies on the effect of food and beverage intake on the gut environment and microbiome and on ... -
Validity of clinical disease activity index (CDAI) to evaluate the disease activity of rheumatoid arthritis patients in Sri Lanka: A prospective follow up study based on newly diagnosed patients
( Public Library of Science , 2022 , Article)Routine use of the Disease Activity Score-28 (DAS28) to assess the disease activity in rheumatoid arthritis (RA) is limited due to its dependency on laboratory investigations and the complex calculations involved. In ... -
The SARS-CoV-2 Spike Protein Activates the Epidermal Growth Factor Receptor-Mediated Signaling
( MDPI , 2023 , Article)The coronavirus disease-19 (COVID-19) pandemic is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At the molecular and cellular levels, the SARS-CoV-2 uses its envelope glycoprotein, the ... -
Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Autism spectrum disorder (ASD) is an umbrella term that encompasses several disabling neurodevelopmental conditions. These conditions are characterized by impaired manifestation in social and communication skills with ... -
Selective Activation of G protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis.
( Bentham Science Publishers , 2023 , Article Review)Atherosclerosis remains a leading contributor to cardiovascular disease-associated morbidity and mortality. Interestingly, the death rate is higher in men than women from atherosclerosis, and the risk increases for ... -
Drug Repurposing in Vasculo-metabolic Diseases
( Bentham Science Publishers , 2023 , Article)Drug repurposing or repositioning is an approach that seeks to maximize the use of existing drugs by identifying new indications other than the ones for which the drug was initially conceived [1-5]. This approach has been ... -
Clinical Phenotypes of PCOS: a Cross-Sectional Study
( Springer , 2023 , Article)This cross-sectional study examines the Doi-Alshoumer PCOS clinical phenotype classification in relation to measured clinical and biochemical characteristics of women with polycystic ovary syndrome (PCOS). Two cohorts of ... -
Prevalence and global trends of polypharmacy in patients with chronic liver disease: A systematic review and meta-analysis
( Wolters Kluwer Health , 2023 , Article)Background: Despite its central role in drug metabolism, the exact prevalence estimates and factors affecting global trends of polypharmacy in patients with chronic liver disease (CLD) have remained unexamined. The aim of ... -
Chronic Wound Healing Models
( American Chemical Society (ACS) , 2023 , Article)In this paper, we review and analyze the commonly available wound healing models reported in the literature and discuss their advantages and issues, considering their relevance and translational potential to humans. Our ... -
Applications of Artificial Intelligence in Thalassemia: A Comprehensive Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Thalassemia is an autosomal recessive genetic disorder that affects the beta or alpha subunits of the hemoglobin structure. Thalassemia is classified as a hypochromic microcytic anemia and a definitive diagnosis of thalassemia ... -
A Bibliometric Analysis and Visualization of Decision Support Systems for Healthcare Referral Strategies
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: The referral process is an important research focus because of the potential consequences of delays, especially for patients with serious medical conditions that need immediate care, such as those with metastatic ... -
Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model
( Elsevier , 2023 , Article)Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ... -
The Association Between Inflammatory Bowel Disease and Exposure to Tobacco Smoking: A Case-Control Study in Qatar
( Dove Medical Press , 2023 , Article)Objective: This research investigated the association between childhood and adulthood tobacco smoking exposure with ulcerative colitis (UC) and Crohn’s disease (CD) in Qatar. Study Design and Setting: In this case-control ... -
The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
( Frontiers Media , 2023 , Article)Background: The cross-protective nature of Bacillus Calmette-Guerin (BCG) vaccine against SARS-CoV-2 virus was previously suggested, however its effect in COVID-19 patients with type 2 diabetes (T2D) and the underlying ... -
An updated overview of cyanidins for chemoprevention and cancer therapy
( Elsevier , 2023 , Article Review)Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ... -
Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
( MDPI , 2023 , Article)Cancer is the second most life-threatening disease and has become a global health and economic problem worldwide. Due to the multifactorial nature of cancer, its pathophysiology is not completely understood so far, which ... -
Association Between Metabolic Syndrome and Decline in Cognitive Function: A Cross-Sectional Study
( Dave Medical Press Limited, , 2023 , Article)Aim: We investigated whether metabolic syndrome (MetS) is associated with a decline in cognitive function in a cohort of middle-aged and elderly individuals without known cognitive dysfunction diseases in Qatar. Methods: ... -
Validation of Doi's weighted average glucose as a measure of post-load glucose excursion for clinical use.
( Biomolecules and Biomedicine , 2023 , Article)In this study, we examined the performance of a novel index of glucose excursion (Doi’s weighted average glucose [dwAG]) in relation to the conventional measure of area under the oral glucose tolerance test (A-GTT) and the ... -
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
( Nature Research , 2023 , Article)Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the ... -
Sickness absenteeism among primary health care workers in Qatar before and during the COVID-19 pandemic
( BioMed Central Ltd , 2023 , Article)Objectives: To explore the patterns, trends, nature, and extent of changes in sickness absence among health care workers (HCWs) at the Primary Health Care Corporation (PHCC) in Qatar-during the COVID-19 pandemic compared ...
