Medicine Research
Recent Submissions
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Gender-Specific Fat Distribution and Association with Type 2 Diabetes Mellitus: A Study of Adiposity Indicators (DEXA, BMI, Waist-to-Hip Ratio) in Adults from Qatar
( Dove Press Ltd , 2024 , Article)Aim: This study aimed to investigate the difference in adiposity measured by DEXA between people with type 2 diabetes mellitus (T2DM) and those without. Moreover, we investigated the most reliable adiposity measure for ... -
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
( Elsevier , 2024 , Article)Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy ... -
Practices and outcomes of responsive caregiving on child neurodevelopment and mental health across diverse global populations: a scoping review protocol.
( BMJ Publishing Group , 2024 , Article)Responsive caregiving (RC) leads to positive outcomes in children, including secure attachment with caregivers, emotional regulation, positive social interactions and cognitive development. Through our scoping review, we ... -
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
( Elsevier , 2024 , Article)In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ... -
Corrigendum to “Morphometric study of the facial skeleton in Jordanians: A computed tomography scan-based study” [Forensic Sci. Int. 302 (2019) 109916] (Forensic Science International (2019) 302, (S0379073819303287), (10.1016/j.forsciint.2019.109916))
( Elsevier Ireland Ltd , 2020 , Article)The authors regret that the affiliation published for Dr. Mohammed Allouh and Heba شis incorrect. The affiliation for Dr. Mohammed Allouh should be: Faculty of Medicine, Jordan University of Science and Technology, Irbid, ... -
Erratum: Software Intervention in Smoking Cessation among Engineering Students in Bhubaneswar City: A Randomized Controlled Trial
( Medknow Publications , 2024 , Other)In the article titled “Assessing the Burden of COVID-19 among Children Aged 6-14 Years in Karnataka, India: A Cross-sectional Survey”, by Padma M Rajagopal, Satyam Sil, Prameela Dinesh, Shilpa Shiju, Arunkumar D P, Srinivas ... -
Assessing the Burden of COVID‑19 among Children Aged 6‑14 Years in Karnataka, India: A Cross‑sectional Survey
( Medknow Publications , 2024 , Article)Background: India experienced three coronavirus disease (COVID-19) waves, with the third attributed to the highly contagious Omicron variant. Before the national vaccination rollout for children above 6, understanding ... -
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
( Frontiers Media , 2024 , Article Review)Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ... -
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
( Elsevier , 2024 , Article)BackgroundAccurate assessments of current and future fertility—including overall trends and changing population age structures across countries and regions—are essential to help plan for the profound social, economic, ... -
Bridging conventional medicine and traditional, complementary, and alternative approaches: Fostering collaborative attempts for a holistic healthcare system
( Elsevier , 2023 , Other)Dear Editor, We read the paper entitled “The future of integrative health: vision, values, and principles for positive, sustainable systemic change” by Kemper, which was published last month.1 The points discussed therein ... -
Dental implant placement with immersive technologies: A preliminary clinical report of augmented and mixed reality applications
( Elsevier , 2024 , Report)A preliminary clinical report of implant placements with 2 immersive reality technologies is described: augmented reality with head mounted display and mixed reality with a tablet PC. Both immersive realities are promising ... -
The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer
( Elsevier , 2023 , Article)IntroductionHER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. It is present in 15 to 20% of breast cancers and is clinically ... -
Vitamin D status affects proteomic profile of HDL-associated proteins and inflammatory mediators in dyslipidemia
( Elsevier , 2024 , Article)Vitamin D deficiency and dyslipidemia have substantial implications for human health globally. Vitamin D is essential for bone metabolism and immune modulation, and its insufficiency is linked to various chronic inflammatory ... -
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
( Elsevier , 2023 , Article)In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type 2 diabetes ... -
The Role of Apolipoproteins in the Commonest Cancers: A Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Apolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the ... -
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
( Springer Nature , 2023 , Article)There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ... -
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
( Elsevier B.V. , 2024 , Article)The unfolded protein response (UPR) detects increased misfolded proteins and activates protein refolding, protein degradation and inflammatory responses. UPR sensors in the endoplasmic reticulum, IRE1α and PERK, bind and ... -
Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): A randomised controlled trial protocol
( BMJ Publishing Group , 2024 , Article)Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion ... -
Validation of plasma protein glycation and oxidation biomarkers for the diagnosis of autism
( Springer Nature , 2023 , Article)Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder in children. It is currently diagnosed by behaviour-based assessments made by observation and interview. In 2018 we reported a discovery study of a ... -
Use of conditional estimates of effect in cancer epidemiology: An application to lung cancer treatment
( Elsevier , 2024 , Article)Background: In oncology clinical trials, there is the assumption that randomization sufficiently balances confounding covariates and therefore average treatment effects are usually reported. This paper explores the wider ...
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