Browsing Faculty Contributions by Author "Elgamal, Mahmoud"
Now showing items 1-6 of 6
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Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
Mousa, Hanaa; Elgamal, Mahmoud; Marei, Reham Ghazal; Souchelnytskyi, Nazariy; Lin, Kah-Wan.; Souchelnytskyi, Serhiy... more authors ... less authors ( International Institute of Anticancer Research , 2019 , Article)Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ... -
Antibacterial activity of Myrtus communis L. and Melaleuca leucadendron var. cajaputi essential oils against antibiotic-resistant bacterial strains
Donadu, Matthew G.; Chowdhury, Shazeda H.; Elgamal, Mahmoud; Usai, Donatella; Zanetti, Stefania; Zughaier, Susu M.... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Antimicrobial resistance (AMR) is a global threat to public health. There is a dire need for new antibiotics as AMR threatens our last-resort antibiotics efficacy. 1,2 Myrtle plants have been used in folk ... -
Development of an in-house COVID-19 serology ELISA Test
Chowdhury, Shazeda; Taleb, Sara; Elgamal, Mahmoud; Hassan, Nesyia; Nomikos, Michail; Hssain, Ali Ait; Zughaier, Susu M... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within ... -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
Gotoh, Takaya; Iwahana, Hiroyuki; Kannan, Surya; Marei, Reham Ghazal; Mousa, Hanaa; Elgamal, Mahmoud; Souchelnytskyi, Serhiy... more authors ... less authors ( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
The role of antibiotic resistance mobile genetic element MCR-1 in enhancing bacterial survival in macrophages
Hashim, Amina; Elgamal, Mahmoud; Chowdhury, Shazeda H.; Hattab, Fatima A.; Al-Shibly, Rafal; Eltai, Nahla; Al-Thani, Asmaa; Zughaier, Susu M.... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Antimicrobial resistance (AMR) determinants such as mobile colistin resistance (MCR-1) that encodes colistin resistance are increasingly spreading in healthcare-associated and community-acquired infections. 1 ... -
Ventilator-associated pneumonia diagnosis: electrochemical sensors for rapid and sensitive detection of pyocyanin
Noorizadeh, Mohammad; Al-Hasan, Tamim M.; Sha, Mizaj S.; Bensaali, Faycal; Meskin, Nader; Sadasivuni, Kishor K.; Zughaier, Susu M.; Elgamal, Mahmoud; Hssain, Ali Ait... more authors ... less authors ( Springer Nature , 2024 , Article)Ventilator-associated pneumonia (VAP) is a severe condition in critically ill patients that requires timely diagnosis to improve patient outcomes. In this study, we developed an electrochemical sensor for pyocyanin detection ...