تصفح Faculty Contributions حسب المؤلف "UDDIN, SHAHAB"
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Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
Queenie, Fernandes; Therachiyil, Lubna; Khan, Abdul Q.; Bedhiafi, Takwa; Korashy, Hesham M; Bhat, Ajaz A.; Uddin, Shahab... more authors ... less authors ( Elsevier , 2023 , Article)Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ... -
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
Sourour, Idoudi; Bedhiafi, Takwa; Sahir, Fairooz; Hijji, Yousef; Uddin, Shahab; Merhi, Maysaloun; Dermime, Said; Billa, Nashiru... more authors ... less authors ( Elsevier , 2023 , Article)Colon cancer (CRC) is the second leading cause of death and the third most diagnosed cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity, it is characterized by its poor solubility, low ... -
Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents
Sheema, Hashem; Ali, Tayyiba Akbar; Akhtar, Sabah; Nisar, Sabah; Sageena, Geetanjali; Ali, Shahid; Al-Mannai, Sharefa; Therachiyil, Lubna; Mir, Rashid; Elfaki, Imadeldin; Mir, Mohammad Muzaffar; Jamal, Farrukh; Masoodi, Tariq; Uddin, Shahab; Singh, Mayank; Haris, Mohammad; Macha, Muzafar; Bhat, Ajaz A.... more authors ... less authors ( Elsevier , 2022 , Article Review)Cancer is one of the leading causes of death and significantly burdens the healthcare system. Due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. The use of natural products as ... -
Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
Kuttikrishnan, Shilpa; Prabhu, Kirti S.; Khan, Abdul Q.; Alali, Feras Q.; Ahmad, Aamir; Uddin, Shahab... more authors ... less authors ( Taylor and Francis Group , 2021 , Article)Forkhead box M1 (FoxM1) is a transcription factor that plays an important role in the etiology of many cancers, however, its role has not been elucidated in B-precursor acute lymphoblastic leukemia (B-pre-ALL). In the ... -
Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development.
Rayan, Menatallah; Sayed, Tahseen S; Hussein, Ola J; Therachiyil, Lubna; Maayah, Zaid H; Maccalli, Cristina; Uddin, Shahab; Prehn, Jochen H M; Korashy, Hesham M... more authors ... less authors ( Springer Nature , 2024 , Article)Gut microbiota regulates various aspects of human physiology by producing metabolites, metabolizing enzymes, and toxins. Many studies have linked microbiota with human health and altered microbiome configurations with the ... -
Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: Potential and challenges
Siveen, Kodappully Sivaraman; Prabhu, Kirti; Krishnankutty, Roopesh; Kuttikrishnan, Shilpa; Tsakou, Magdalini; Alali, Feras Q.; Dermime, Said; Mohammad, Ramzi M.; Uddin, Shahab... more authors ... less authors ( Bentham , 2017 , Article)Angiogenesis is defined as the physiological process by which new blood vessels develop from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis is one of the most encouraging strategies ...