Browsing Faculty Contributions by Subject "Consanguinity"
Now showing items 1-7 of 7
-
The Arab genome: Health and wealth
( Elsevier B.V. , 2016 , Article)The 22 Arab nations have a unique genetic structure, which reflects both conserved and diverse gene pools due to the prevalent endogamous and consanguineous marriage culture and the long history of admixture among different ... -
Burden of Mendelian disorders in a large Middle Eastern biobank
(2024 , Article)Background: Genome sequencing of large biobanks from under-represented ancestries provides a valuable resource for the interrogation of Mendelian disease burden at world population level, complementing small-scale familial ... -
Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries.
( Current Medicine Group , 2016 , Article)Type 1 diabetes (T1D) is a complex autoimmune disorder that results from the T cell-mediated destruction of the pancreatic β cells and is due to interactions between environmental and genetic factors. Although Arabs have ... -
Genetic epidemiology of Woodhouse-Sakati Syndrome in the Greater Middle East region and beyond: a systematic review
( BioMed Central Ltd , 2023 , Article Review)Background: Woodhouse-Sakati syndrome (WSS) is a rare, autosomal recessive genetic disorder with variable clinical manifestations mainly affecting the endocrine and nervous systems. The aim of this study was to systematically ... -
Potential causes of male and female infertility in Qatar
( Elsevier , 2020 , Article Review)A steady decline in the fertility rate has been observed in Qatar during the past fifty years. Therefore, infertility is considered a national priority in Qatar, a pronatalist society. This review article summarises the ... -
The prevalence of attention deficit hyperactivity symptoms in schoolchildren in a highly consanguineous community
( Karger , 2008 , Article)Objective: The objective of the present study was to find the prevalence of attention deficit hyperactivity (ADH) symptoms in a sample of primary schoolchildren in Qatar and investigate the behaviour of the children with ... -
The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar
( S. Karger AG , 2022 , Article)Introduction: Monogenic obesity (MO) is a rare genetic disease characterized by severe early-onset obesity in affected individuals. Previous genetic studies revealed 8 definitive genes for monogenic non-syndromic obesity; ...