Browsing Faculty Contributions by Subject "1"

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Evaluation of 2-(1H-1,2,3-Triazol-1-yl) acetic acid derivatives as potential human hypoxia-inducible factor (HIF) prolyl hydroxylase domain-2 (PHD2) inhibitors

Sayaf, Abrar Mohammad; Cheah, June Sun; Khan, Abbas; Schofield, Christopher J.; Agouni, Abdelali; Yeoh, Kar Kheng... more authors ... less authors ( Walter de Gruyter GmbH , 2025 , Article)
The hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD) inhibitors can potentially treat ischemic and hypoxic-related diseases, as demonstrated by their use in anemia treatment. An AlphaScreen assay was utilized ...