Browsing Faculty Contributions by Subject "Breast cancer"
Now showing items 1-20 of 55
-
3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy
( Elsevier B.V. , 2021 , Article)The bioprinting technique with specialized tissue production allows the study of biological, physiological, and behavioral changes of cancerous and non-cancerous tissues in response to pharmacological compounds in personalized ... -
A simple model for cell type recognition using 2D-correlation analysis of FTIR images from breast cancer tissue
( Elsevier B.V. , 2018 , Article)Breast cancer is the second most common cancer after lung cancer. So far, in clinical practice, most cancer parameters originating from histopathology rely on the visualization by a pathologist of microscopic structures ... -
Acinic cell carcinoma of the breast: A comprehensive review
( Elsevier , 2022 , Article)Acinic cell carcinoma of the breast is a rare special subtype of breast cancer in the category of salivary gland-type tumors. It is morphologically similar to acinic cell carcinomas of salivary glands and pancreas and has ... -
Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
( International Institute of Anticancer Research , 2019 , Article)Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ... -
Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Production
( Public Library of Science , 2013 , Article)Background: We have recently reported that Origanum majorana exhibits anticancer activity by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer cell line. Here, we extended our study by ... -
Antimetastatic Activity of Lactoferrin-Coated Mesoporous Maghemite Nanoparticles in Breast Cancer Enabled by Combination Therapy
( American Chemical Society , 2020 , Article)Despite successes in breast cancer treatment, the incidence of metastasis, drug resistance, and toxicity limit the efficacy of current therapeutic modalities. Herein, by designing lactoferrin-doxorubicin-mesoporous maghemite ... -
Apocrine Carcinoma
( Springer, Cham , 2017 , Book chapter)Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” ... -
The assessment of tumor-infiltrating lymphocytes in invasive apocrine carcinoma of the breast in relation to the HER2 status.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2023 , Article)In the current study, we assessed the prevalence and molecular features of HER2-low phenotype in the apocrine carcinomas of the breast (ApoCa) and its relationship with tumor-infiltrating lymphocytes (TILs). A cohort of ... -
Breast cancer health promotion in Qatar: A survey of community pharmacists' interests and needs
( Springer Nature , 2013 , Article)Objectives Breast cancer is the most common cancer in women in Qatar. Despite the sustained efforts to increase breast cancer public awareness via campaigns and public screening programmes, breast cancer screening rate ... -
Breast cancer image classification using pattern-based Hyper Conceptual Sampling method
( Elsevier Ltd , 2018 , Article)The increase in biomedical data has given rise to the need for developing data sampling techniques. With the emergence of big data and the rise of popularity of data science, sampling or reduction techniques have been ... -
Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes.
( Elsevier , 2018 , Article)The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with ... -
BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes
( BioScientifica Ltd. , 2018 , Article)In Oman, breast cancer is most common, representing approximately more than 25% of all cancers in women. Relatively younger populations of patients (25-40 years) present surprisingly with an aggressive phenotype and advanced ... -
Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired
( BioMed Central Ltd , 2023 , Article Review)Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the ... -
Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer
( Public Library of Science , 2014 , Article)Background: In this study we investigated the in vitro and in vivo anticancer effect of carnosol, a naturally occurring polyphenol, in triple negative breast cancer.Results: We found that carnosol significantly inhibited ... -
CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion.
(2017 , Article)We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized the players underlying their separate signaling ... -
Chapter Four Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach
( Elsevier , 2023 , Book chapter)Cyclin-dependent kinase 6 (CDK6) is an essential kinase in cell cycle progression, which is a viable target for inhibitors in various malignancies, including breast cancer. This study aimed to virtually screen efficient ... -
The characteristics and prognostic significance of histone H1 expression in breast cancer
( Elsevier , 2024 , Article)Histone H1 (H.H1) is involved in chromatin organisation and gene regulation and is overexpressed in many malignant tumours, including breast cancer (BC). This study proposed and evaluated the prognostic role of H.H1 ... -
Comment on the manuscript “Histological subtype is associated with PD-L1 expression and CD8+ T-cell infiltrates in triple-negative breast carcinoma” by Salisbury et al. (Ann Diagn Pathol 2022; 57: 151901, https://doi.org/10.1016/j.anndiagpath.2022.151901)
( Elsevier , 2022 , Other)I read with great interest a recent paper written by Salisbury et al. published in the April 2022 issue of the Annals of Diagnostic Pathology [1]. In their study, the authors explored a small cohort of triple-negative ... -
Contribution of Glycosaminoglycan binding in CCL21-mediated Migration of Breast Cancer cells
( Qatar University Press , 2021 , Poster)Lymph node metastasis constitutes a key event in Breast Cancer progression and it is a process at least partially mediated by the chemokine CCR7. Chemokine function is dependent upon their binding to both cell-surface ... -
Cost-effectiveness analyses of breast cancer medications use in developing countries: a systematic review
( Taylor and Francis Ltd. , 2020 , Article)Background: Pharmacoeconomics is important for breast-cancer medications due to their high costs. To our knowledge, no systematic literature reviews of pharmacoeconomic studies for breast-cancer medication use are present ...