Browsing Faculty Contributions by Subject "Consanguinity"

Now showing items 1-7 of 7

    • The Arab genome: Health and wealth 

      Zayed, Hatem ( Elsevier B.V. , 2016 , Article)
      The 22 Arab nations have a unique genetic structure, which reflects both conserved and diverse gene pools due to the prevalent endogamous and consanguineous marriage culture and the long history of admixture among different ...

    • Burden of Mendelian disorders in a large Middle Eastern biobank 

      Aamer, Waleed; Al-Maraghi, Aljazi; Syed, Najeeb; Gandhi, Geethanjali Devadoss; Aliyev, Elbay; ... more authors (2024 , Article)
      Background: Genome sequencing of large biobanks from under-represented ancestries provides a valuable resource for the interrogation of Mendelian disease burden at world population level, complementing small-scale familial ...

    • Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries. 

      Zayed, Hatem ( Current Medicine Group , 2016 , Article)
      Type 1 diabetes (T1D) is a complex autoimmune disorder that results from the T cell-mediated destruction of the pancreatic β cells and is due to interactions between environmental and genetic factors. Although Arabs have ...

    • Genetic epidemiology of Woodhouse-Sakati Syndrome in the Greater Middle East region and beyond: a systematic review 

      Kohil, Amira; Abdallah, Atiyeh M.; Hussain, Khalid; Al-Shafai, Mashael ( BioMed Central Ltd , 2023 , Article Review)
      Background: Woodhouse-Sakati syndrome (WSS) is a rare, autosomal recessive genetic disorder with variable clinical manifestations mainly affecting the endocrine and nervous systems. The aim of this study was to systematically ...

    • Potential causes of male and female infertility in Qatar 

      Gerhild, Zauner; Girardi, Guillermina ( Elsevier , 2020 , Article Review)
      A steady decline in the fertility rate has been observed in Qatar during the past fifty years. Therefore, infertility is considered a national priority in Qatar, a pronatalist society. This review article summarises the ...

    • The prevalence of attention deficit hyperactivity symptoms in schoolchildren in a highly consanguineous community 

      Bener, Abdulbari; Al Qahtani, Razna; Teebi, Ahmad S.; Bessisso, Mohammed ( Karger , 2008 , Article)
      Objective: The objective of the present study was to find the prevalence of attention deficit hyperactivity (ADH) symptoms in a sample of primary schoolchildren in Qatar and investigate the behaviour of the children with ...

    • The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar 

      Abouhashem, Nadien; Zaied, Roan E.; Al-Shafai, Kholoud; Nofal, Mariam; Syed, Najeeb; ... more authors ( S. Karger AG , 2022 , Article)
      Introduction: Monogenic obesity (MO) is a rare genetic disease characterized by severe early-onset obesity in affected individuals. Previous genetic studies revealed 8 definitive genes for monogenic non-syndromic obesity; ...