Browsing Faculty Contributions by Subject "exome sequencing"

Now showing items 1-2 of 2

    • The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap 

      Abdallah, Atiyeh M.; Abu-Madi, Marawan ( Frontiers Media , 2021 , Article Review)
      Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ...

    • Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes 

      George, Hindy; Dornbos, Peter; Chaffin, Mark D.; Liu, Dajiang J.; Wang, Minxian; ... more authors ( Elsevier , 2022 , Article)
      Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele ...