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Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials
(
Elsevier
, 2023 , Article)
AimsWeight reduction is fundamental for the management and remission of diabetes. We aimed to assess ethnic differences in the effects of lifestyle weight-loss interventions on HbA1c levels in overweight or obese adults ...
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
(
Elsevier
, 2021 , Article)
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ...
Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
(
Elsevier
, 2023 , Article)
AimCardiac autonomic neuropathy (CAN) has been suggested to be associated with hypoglycemia and impaired hypoglycemia unawareness. We have assessed the relationship between CAN and extensive measures of glucose variability ...
Clinical characteristics of 51,815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings: Priority populations for vaccination
(
Elsevier
, 2021 , Article)
We read with interest Brendish et al. study on the comparison between patients with SARS-CoV-2 positive and negative swab results.1
The study compared the clinical characteristics of adult hospitalised patients with ...
Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin ...
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
The abnormal accumulation of methylglyoxal (MG) leading to increased glycation of protein and DNA has emerged as an important metabolic stress, dicarbonyl stress, linked to aging, and disease. Increased MG glycation produces ...
The association between screen time and depression symptoms severity among adults with diabetes: A cross-sectional study
(
Elsevier
, 2023 , Article)
ObjectiveTo investigate the association between time spent on screen-based sedentary behavior (SBSB) and depression symptom severity (DSS) among adults with type 2 diabetes. MethodsA cross-sectional study employing secondary ...
Performance of artificial intelligence models in estimating blood glucose level among diabetic patients using non-invasive wearable device data
(
Elsevier
, 2023 , Article)
Introduction: Diabetes Mellitus (DM) is characterized by impaired ability to metabolize glucose for use in cells for energy, resulting in high blood sugar (hyperglycemia). DM impacted 463 million individuals worldwide in ...