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السجلات المعروضة 191 -- 200 من 1196
Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications
(
Elsevier
, 2023 , Article)
Due to the strong association between diabetes and cancer incidents, several anti-diabetic drugs, including metformin, have been examined for their anticancer activity. Metformin is a biguanide antihyperglycemic agent used ...
First report of the International Council of Cardiovascular Prevention and Rehabilitation’s Registry (ICRR)
(
Taylor and Francis Ltd.
, 2023 , Article)
Objectives: Cardiac rehabilitation–programs comprehensively delivering outpatient secondary prevention–is under-available and under-studied in the resource-poor settings where it is needed most. This report summarizes the ...
Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma
(
National library of medicine
, 2023 , Article)
Introduction: Osteosarcoma is a rare disorder among cancer, but the most frequently occurring among sarcomas in children and adolescents. It has been reported to possess the relapsing capability as well as accompanying ...
The outcomes of auto-transplanted premolars in the anterior maxilla following traumatic dental injuries
(
Wiley-Blackwell
, 2023 , Article)
Background/Aims: Tooth auto-transplantation is a treatment option, which is often not considered to replace anterior maxillary incisors in children and adolescents. There are multiple prognostic factors that may influence ...
Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
(
Taylor and Francis Ltd.
, 2023 , Article)
Purpose: Low bicarbonate, a hallmark of metabolic acidosis is associated with various diseases. This study investigated associations between bicarbonate levels with prediabetes and subclinical inflammation among healthy ...
Effect of lifestyle intervention on HbA1c levels in overweight and obese adults with type 2 diabetes across ethnicities: A systematic review and meta-analysis of randomized controlled trials
(
Elsevier
, 2023 , Article)
AimsWeight reduction is fundamental for the management and remission of diabetes. We aimed to assess ethnic differences in the effects of lifestyle weight-loss interventions on HbA1c levels in overweight or obese adults ...
Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions
(
Elsevier
, 2023 , Article)
Background: Herpes simplex virus type 2 (HSV-2) infection is a globally prevalent, life-long, sexually transmitted infection. This study characterized HSV-2 seroprevalence in Europe for various at-risk populations and ...
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
(
Elsevier
, 2023 , Article)
BackgroundThe burden of heart failure (HF) is high globally, but information on its burden in the Eastern Mediterranean Region (EMR) is limited. This study provides a systematic analysis of the burden and underlying causes ...
Applications of Machine Learning in Chronic Myeloid Leukemia
(
MDPI
, 2023 , Article)
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by dysregulated growth and the proliferation of myeloid cells in the bone marrow caused by the BCR-ABL1 fusion gene. Clinically, CML demonstrates ...
ANO4 Expression Is a Potential Prognostic Biomarker in Non-Metastasized Clear Cell Renal Cell Carcinoma
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Background: Over the past decade, transcriptome profiling has elucidated many pivotal pathways involved in oncogenesis. However, a detailed comprehensive map of tumorigenesis remains an enigma to solve. Propelled research ...