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Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
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Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ...
Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
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Frontiers Media S.A.
, 2021 , Article)
A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it contributes to energy homeostasis and provides insulation for internal organs. Adipocytes were previously thought to be a passive ...
Proatherogenic sialidases and desialylated lipoproteins: 35 years of research and current state from bench to bedside
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Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
This review summarizes the main achievements in basic and clinical research of atheroscle-rosis. Focusing on desialylation as the first and the most important reaction of proatherogenic pathological cascade, we speak of ...
Pharmacological and antioxidant activities of rhus coriaria l. (sumac)
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Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in ...
Adipose tissue immunomodulation: A novel therapeutic approach in cardiovascular and metabolic diseases
(
Frontiers Media
, 2020 , Article)
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As the main storage pool of lipids, ...
Recent advances in nanotherapeutics for multiple myeloma
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Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Anticancer therapies cannot be included in a one-size-fits-all scenario; it is imperative to adapt therapies to the tumor molecular profile and most importantly to develop target-specific therapeutics. Nanotherapeutics can ...
Covid-19 in pediatric patients: A focus on CHD patients
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Frontiers Media S.A.
, 2020 , Article)
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ...
Hydroxychloroquine in COVID-19 Patients: Pros and Cons
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Frontiers Media S.A.
, 2020 , Article)
The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach ...
Carnosol Is a Novel Inhibitor of p300 Acetyltransferase in Breast Cancer
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Frontiers Media S.A.
, 2021 , Article)
Carnosol, a natural polyphenol abundant in edible plants such as sage, rosemary, and oregano, has shown promising anticancer activity against various types of cancers. Nonetheless, very little is known about its molecular ...
Drug repurposing in neurodegenerative and cardiovascular diseases
(
Bentham Science Publishers
, 2021 , Other)
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