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Now showing items 5741-5750 of 5774
A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
(
Elsevier
, 2019 , Article)
DNA repair mechanism is a process through which the cell repairs its damaged DNA. Although there are several mechanisms involved in the DNA repair mechanisms, the direct reversal method is the simplest and does not require ...
A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
(
Elsevier
, 2017 , Article)
Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its ...
Robust estimation of highly-varying nonlinear instantaneous frequency of monocomponent signals using a lower-order complex-time distribution
(
Elsevier B.V.
, 2013 , Article)
This paper proposes an approach for robust estimation of highly-varying nonlinear instantaneous frequency (IF) in monocomponent nonstationary signals. The proposed method is based on a lower order complex-time distribution ...
Canavan disease: an Arab scenario.
(
Elsevier Inc.
, 2015 , Article)
The autosomal recessive Canavan disease (CD) is a neurological disorder that begins in infancy. CD is caused by mutations in the gene encoding the ASPA enzyme. It has been reported with high frequency in patients with ...
Patient-dentist relationship and dental anxiety among young Sudanese adult patients
(
Elsevier
, 2019 , Article)
Objective: To evaluate the effects of the patient–dentist relationship on dental anxiety among young adult Sudanese patients. Materials and methods: In this cross-sectional study, 864 patients attending outpatient dental ...
Hospital effect on infections after four major surgeries: Outlier and volume-outcome analysis using all-inclusive state data
(
Elsevier
, 2017 , Article)
Hospital volume is known to have a direct impact on outcomes of major surgeries. However, it is unclear if the evidence applies specifically to surgical site infections. To determine if there are procedure-specific hospital ...
Effectiveness of Different Topical Treatments in the Healing of Pressure Injuries: A Network Meta-analysis.
(
Elsevier
, 2018 , Article)
Pressure injuries (PIs) are one of the most common types of complex wounds and impose a huge economic burden on the healthcare system and the patients. A plethora of topical treatments is widely available for PI treatment, ...
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
(
Elsevier
, 2019 , Article)
To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ...
PD-L1 status in breast cancer: Current view and perspectives.
(
Elsevier
, 2019 , Article)
Breast cancer was traditionally not considered a particularly immunogenic tumor. However, recent developments have shown that some aggressive triple-negative breast cancers are immunogenic, exhibit a resistance to chemotherapy ...
Impact of a Collaborative Pharmaceutical Care Service Among Patients With Diabetes in an Ambulatory Care Setting in Qatar: A Multiple Time Series Study
(
Elsevier
, 2019 , Article)
Background
Diabetes mellitus is highly prevalent in the Middle East and the burden associated with it is dramatically increasing. Pharmacists working in collaborative healthcare teams have an important role to improve ...