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Now showing items 641-650 of 783
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
(
Springer
, 2023 , Article Review)
Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ...
Biochemical and cellular basis of oxidative stress: Implications for disease onset
(
Wiley
, 2023 , Article Review)
Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ...
Emergent properties of microbial activity in heterogeneous soil microenvironments: Different research approaches are slowly converging, yet major challenges remain
(
Frontiers Media S.A.
, 2018 , Article Review)
Over the last 60 years, soil microbiologists have accumulated a wealth of experimental data showing that the bulk, macroscopic parameters (e.g., granulometry, pH, soil organic matter, and biomass contents) commonly used ...
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
(
MDPI
, 2015 , Article Review)
Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ...
Immunotherapy and immunoevasion of colorectal cancer
(
Elsevier
, 2023 , Article Review)
The tremendous success of immunotherapy in clinical trials has led to its establishment as a new pillar of cancer therapy. However, little clinical efficacy has been achieved in microsatellite stable colorectal cancer ...
Deep visual social distancing monitoring to combat COVID-19: A comprehensive survey
(
Elsevier Ltd
, 2022 , Article Review)
Since the start of the COVID-19 pandemic, social distancing (SD) has played an essential role in controlling and slowing down the spread of the virus in smart cities. To ensure the respect of SD in public areas, visual SD ...
THE SULTAN AND THE REBEL: SAʿDUN AL-MANSUR'S REVOLT IN THE MUNTAFIQ, C. 1891-1911
(
Cambridge University Press
, 2013 , Article Review)
From 1891 to 1911, a disenfranchised shaykh of the Muntafiq tribe, Saʿdun al-Mansur, led a large uprising against Ottoman rule in southern Iraq. Feeling that he had been disinherited from properties that were his birthright, ...
A comprehensive review of power flow controllers in interconnected power system networks
(
Institute of Electrical and Electronics Engineers Inc.
, 2020 , Article Review)
Energy security is one of the most crucial factor in the development of any nation. Interconnections among different power system networks are made to lower the overall price of power generation as well as enhance the ...
Genomic and Bioinformatics Approaches for Analysis of Genes Associated With Cancer Risks Following Exposure to Tobacco Smoking
(
Frontiers Media S.A.
, 2018 , Article Review)
Cancer is a significant health problem in the Middle East and global population. It is well established that there is a direct link between tobacco smoking and cancer, which will continue to pose a significant threat to ...
Reactive oxygen species: Modulators of phenotypic switch of vascular smooth muscle cells
(
MDPI
, 2020 , Article Review)
Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling. However, high ROS levels cause oxidative stress, which is implicated ...