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A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing
(
Springer Verlag
, 2021 , Article Review)
Coronavirus disease (COVID-19) pandemic is instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of March 13, 2021, more than 118.9 million cases were infected with COVID-19 worldwide. SARS-CoV-2 ...
Genetic polymorphisms associated with obesity in the Arab world: a systematic review
(
Springer Nature
, 2021 , Article Review)
Background: Obesity, one of the most common chronic health conditions worldwide, is a multifactorial disease caused by complex genetic and environmental interactions. Several association studies have revealed a considerable ...
Assessing left ventricular systolic function by emergency physician using point of care echocardiography compared to expert: systematic review and meta-analysis.
(
Lippincott, Williams & Wilkins
, 2021 , Article Review)
Assessing left ventricular systolic function (LVSF) by echocardiography assists in the diagnosis and management of a diverse range of patients presenting to the emergency department (ED). We evaluated the agreement between ...
Interrelation between Sleep Bruxism and Obstructive Sleep Apnea: Literature Review
(
Hooghly Sciencedomain International
, 2021 , Article Review)
Obstructive sleep apnea (OSA) is a clinical risk factor for sleep bruxism (SB). Although no clear causative link has been defined, both conditions are inter related to sleep-related arousal reactions. A literature review ...
Pleiotropic role of notch signaling in human skin diseases
(
MDPI
, 2020 , Article Review)
Notch signaling orchestrates the regulation of cell proliferation, differentiation, migration and apoptosis of epidermal cells by strictly interacting with other cellular pathways. Any disruption of Notch signaling, either ...
Hiv-1 infection transcriptomics: Meta-analysis of cd4+ t cells gene expression profiles
(
MDPI
, 2021 , Article Review)
HIV-1 infection elicits a complex dynamic of the expression various host genes. High throughput sequencing added an expressive amount of information regarding HIV-1 infections and pathogenesis. RNA sequencing (RNA-Seq) is ...
Microwave-assisted palladium-catalyzed cross-coupling reactions: Generation of carbon-carbon bond
(
MDPI
, 2020 , Article Review)
Cross-coupling reactions furnishing carbon–carbon (C–C) bond is one of the most challenging tasks in organic syntheses. The early developed reaction protocols by Negishi, Heck, Kumada, Sonogashira, Stille, Suzuki, and ...
Multiomics integration in skin diseases with alterations in notch signaling pathway: PlatOMICs phase 1 deployment
(
MDPI
, 2021 , Article Review)
The high volume of information produced in the age of omics was and still is an important step to understanding several pathological processes, providing the enlightenment of complex molecular networks and the identification ...
Lipid transfer proteins (Ltps)- structure, diversity and roles beyond antimicrobial activity
(
MDPI
, 2021 , Article Review)
Lipid transfer proteins (LTPs) are among the most promising plant-exclusive antimicrobial peptides (AMPs). They figure among the most challenging AMPs from the point of view of their structural diversity, functions and ...
Comparison of immunogenicity and safety of licensed Japanese encephalitis vaccines: A systematic review and network meta-analysis
(
Elsevier
, 2021 , Article Review)
IntroductionAnnually more than 100,000 Japanese encephalitis (JE) cases and 25,000 deaths worldwide are caused by JE virus infection. More than 15 JE vaccines are currently in use worldwide. It is unknown whether any of ...