Search
Now showing items 1-10 of 37
The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Autophagy is a homeostatic process that regulates and recycles intracellular structures and is a host defense mechanism that facilitates bacterial clearance. Uric ...
Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury
(
Scientific Research Publishing
, 2019 , Article Review)
Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
(
MDPI AG
, 2019 , Article)
Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ...
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet.
(
BMC
, 2020 , Article)
Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates ...
Effect of statins on abdominal aortic aneurysm
(
Elsevier
, 2022 , Article Review)
Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ...
Correction to: Lead nitrate induces inflammation and apoptosis in rat lungs through the activation of NF‑κB and AhR signaling pathways (Environmental Science and Pollution Research, (2022), 29, 43, (64959-64970), 10.1007/s11356-022-19980-8)
(
Springer
, 2022 , Article)
The sizing of images Figs. 3 and 4 is modified in the original published proof. The Original article has been corrected.
Sesamol: A lignan in sesame seeds with potent anti-inflammatory and immunomodulatory properties
(
Elsevier
, 2023 , Article)
Inflammation is associated with the development and progression of a plethora of diseases including joint, metabolic, neurological, hepatic, and renal disorders. Sesamol, derived from the seeds of Sesamum indicum L., has ...
The Role of Surface Chemistry in the Osseointegration of PEEK Implants
(
American Chemical Society
, 2022 , Article)
Poly(etheretherketone) (PEEK) implants suffer from poor osseointegration because of chronic inflammation. In this study, we hypothesized that adding NH2and COOH groups to the surface of PEEK could modulate macrophage ...
Mutual inter-regulation between iNOS and TGF-β1: Possible molecular and cellular mechanisms of iNOS in wound healing.
(
Elsevier
, 2020 , Article)
Abnormal wound healing with excessive scarring is a major health problem with socioeconomic and psychological impacts. In human, chronic wounds and scarring are associated with upregulation of the inducible nitric oxide ...
Connecting the dots between PubMed abstracts
(
Public Library of Science
, 2012 , Article)
Background: There are now a multitude of articles published in a diversity of journals providing information about genes, proteins, pathways, and diseases. Each article investigates subsets of a biological process, but to ...