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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Autophagy is a homeostatic process that regulates and recycles intracellular structures and is a host defense mechanism that facilitates bacterial clearance. Uric ...
Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders
(
Society for Biomedical Diabetes Research
, 2019 , Article)
BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ...
Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury
(
Scientific Research Publishing
, 2019 , Article Review)
Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...
Do inflammasome impact COVID-19 severity?
(
Springer
, 2021 , Article Review)
COVID-19 pandemic has proven to be a dramatic challenge, introducing huge clinical differences that demand extensive investigations. Severe and critical patients may present coagulopathies and microthrombi, which results ...
The Role of Surface Chemistry in the Osseointegration of PEEK Implants
(
American Chemical Society
, 2022 , Article)
Poly(etheretherketone) (PEEK) implants suffer from poor osseointegration because of chronic inflammation. In this study, we hypothesized that adding NH2and COOH groups to the surface of PEEK could modulate macrophage ...
Chronotherapy of Non-Steroidal Anti-Inflammatory Drugs May Enhance Postoperative Recovery
(
Nature Research
, 2020 , Article)
Postoperative pain relief is crucial for full recovery. With the ongoing opioid epidemic and the insufficient effect of acetaminophen on severe pain; non-steroidal anti-inflammatory drugs (NSAIDs) are heavily used to ...
Inflammation resolution in environmental pulmonary health and morbidity
(
Elsevier
, 2022 , Other)
NA
Progressive circuit resistance training improves inflammatory biomarkers and insulin resistance in obese men
(
Elsevier Inc.
, 2019 , Article)
Circuit resistance training (CRT) is a time-efficient exercise modality for improving skeletal muscle and cardiovascular fitness. But the beneficial role of CRT in obese individuals is still not well understood. This study ...
Independent and combined effects of antioxidant supplementation and circuit resistance training on selected adipokines in postmenopausal women
(
Frontiers Media
, 2019 , Article)
We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. Forty-eight postmenopausal women ...
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
(
MDPI
, 2020 , Article)
Among the primary contributors to cardiovascular diseases are inflammation and oxidative imbalance within the vessel walls as well as the fibrosis of rat aortic smooth muscle cell (RASMC). Bradykinin (BK) and leptin are ...