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High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury
(
Elsevier
, 2023 , Article)
AimsTraumatic brain injury (TBI) constitutes a serious public health concern. Although TBI targets the brain, it can exert several systemic effects which can worsen the complications observed in TBI subjects. Currently, ...
The 4-hydroxynonenal mediated oxidative damage of blood proteins and lipids involves secondary lipid peroxidation reactions
(
Spandidos Publications
, 2018 , Article)
Lipid peroxidation is associated with several metabolic diseases. Lipid peroxidation causes cellular damage through reactive aldehyde species such as 4-hydroxyonenal (4-HNE). The exact mechanism(s) by which 4-HNE causes ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
(
Elsevier
, 2020 , Article Review)
Traumatic brain injury (TBI) is a global health burden and a major cause of disability and mortality. An early cascade of physical and structural damaging events starts immediately post-TBI. This primary injury event ...
Effect of statins on abdominal aortic aneurysm
(
Elsevier
, 2022 , Article Review)
Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ...
Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
(
Elsevier Ireland Ltd
, 2021 , Article)
Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. This study was designed to investigate the mode of action ...
Herbal medicine for slowing aging and aging-associated conditions: Efficacy, mechanisms and safety
(
Bentham
, 2020 , Article)
Aging and aging-associated diseases are issues with unsatisfactory answers in the medical field. Aging causes important physical changes which, even in the absence of the usual risk factors, render the cardiovascular system ...
Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics
(
Springer Nature
, 2022 , Book chapter)
Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was first discovered ...
Halophytes as important sources of antioxidants and anti-cholinesterase compounds
(
Springer International Publishing
, 2021 , Book chapter)
Halophytes are plants adapted to high salinity, and they are common in many places around the world where environmental conditions are inconvenient for the growth of conventional plants. Normally, plants exposed to harsh ...
A new perspective on cardiovascular drift during prolonged exercise
(
Elsevier Inc.
, 2021 , Article)
Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. Cardiovascular drift has been debated for a long time. Although the ...