Search
Now showing items 1-10 of 17
Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
(
BMC
, 2020 , Article)
© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ...
Many meta-analyses of rare events in the Cochrane Database of Systematic Reviews were underpowered
(
Elsevier
, 2021 , Article)
Background and ObjectiveMeta-analysis is a statistical method with the ability to increase the power for statistical inference, while it may still face the problem of being underpowered. In this study, we investigated the ...
Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives
(
Wiley Open Access
, 2020 , Article)
© 2020 The Authors. Health Science Reports published by Wiley Periodicals LLC. Meta-analyses have been increasingly used to synthesize proportions (eg, disease prevalence) from multiple studies in recent years. Arcsine-based ...
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
(
Elsevier
, 2019 , Article)
To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ...
A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies
(
Elsevier
, 2021 , Article)
ObjectiveIn evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare practice. We ...
Utilization of the evidence from studies with no events in meta-analyses of adverse events: an empirical investigation
(
Springer
, 2021 , Article)
Zero-events studies frequently occur in systematic reviews of adverse events, which consist of an important source of evidence. We aimed to examine how evidence of zero-events studies was utilized in the meta-analyses of ...
The odds ratio is “portable” but not the relative risk: Time to do away with the log link in binomial regression
(
Elsevier
, 2021 , Article)
Objectives: In a recent paper we suggest that the relative risk (RR) be replaced with the odds ratio (OR) as the effect measure of choice in clinical epidemiology. In response, Chu, and colleagues raise several points that ...
Rapid evidence synthesis approach for limits on the search date: how rapid could it be?
(
John Wiley and Sons
, 2021 , Article)
Rapid reviews have been widely employed to support timely decision-making, and limiting the search date is the most popular approach in published rapid reviews. We assessed the accuracy and workload of search date limits ...
Empirical Comparisons of 12 Meta-analysis Methods for Synthesizing Proportions of Binary Outcomes
(
Springer
, 2021 , Article)
Background: Meta-analysis is increasingly used to synthesize proportions (e.g., disease prevalence). It can be implemented with widely used two-step methods or one-step methods, such as generalized linear mixed models ...
Synthesis of evidence from zero-events studies: A comparison of one-stage framework methods
(
John Wiley & Sons, Ltd
, 2021 , Article)
In evidence synthesis, dealing with zero-events studies is an important and complicated task that has generated broad discussion. Numerous methods provide valid solutions to synthesizing data from studies with zero-events, ...